Results 91 to 100 of about 3,374 (156)

Conotoxins that may be involved in gene recombination events.

, 2013
Conotoxins that may be involved in gene recombination events.
Lei Wang (6656), Maojun Zhou (497339), Yuwen You (497340), Yun Wu (150224), Yuanyuan Qiang (497341), Shaonan Luo (497343), Mengying Qin (497342), Xiaoyan Zhu (261366), Anlong Xu (24151), Zhenghua Ren (497344)   +9 more
core   +1 more source

Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors

, 2021
The short disulfide-rich α-conotoxins derived from the venom of Conus snails comprise a conserved CICII(m)CIII(n)CIV cysteine framework (m and n, number of amino acids) and the majority antagonize nicotinic acetylcholine receptors (nAChRs).
Paul F Alewood (20218596), David J Adams (8273148), Han Shen Tae (20023188), Bingmiao Gao (5570840), Ai Hua Jin (20273622)   +4 more
core   +1 more source

Predatory and Defensive Strategies in Cone Snails

Toxins
Cone snails are carnivorous marine animals that prey on fish (piscivorous), worms (vermivorous), or other mollusks (molluscivorous). They produce a complex venom mostly made of disulfide-rich conotoxins and conopeptides in a compartmentalized venom gland.
Zahrmina Ratibou, Nicolas Inguimbert, Sébastien Dutertre   +2 more
doaj   +1 more source

Mass Spectrometry-based Sequencing of Venom Peptides (Conotoxins) from Vermivorous Cone Snail, Conus Loroisii: Toxicity of its Natural Venom

, 2021
Conus loroisii is a marine vermivorous snail found profusely in the southern seas of India. They harbor several toxic peptide components commonly called as ‘conotoxins’. In this study, we have identified and sequenced five conotoxins using proteome based
Syed, Humaira Saleh, Selvam, M Masilamani, R, Rishimol, J, Arun Kumar, P, Rajesh R   +4 more
core  

The Conopeptide αD-FrXXA, an Inhibitor of Voltage-Gated Potassium Channels

Marine Drugs
The conopeptide αD-FrXXA was previously isolated by our team from the venom of the vermivorous snail Conus fergusoni. This toxin is composed of two chains of 47 amino acids and inhibits neuronal and muscular subtypes of nAChR.
Luis Martínez-Hernández, Estuardo López-Vera, Ximena C. Rodriguez-Ruiz, Mónica A. Ortíz-Arellano   +3 more
doaj   +1 more source

a-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses

, 2020
a-Conotoxins are selective antagonists of neuromuscular or neuronal nicotinic acetylcholine receptors. Individual family members are often highly selective towards distinct receptor subclasses, most notably within neuronal nicotinic acetylcholine ...
Robert W Janes, Ronald Hogg, Daniel Bertrand   +2 more
core  

From Marine Peptides to Oncology: The Therapeutic Potential of Conotoxins in Cancer Treatment. [PDF]

Chem Biodivers
Awais S, Javed MA, Ali R, Shahid M, Shahid MA, Masaud H, Ali N.   +6 more
europepmc   +1 more source

Structural and functional basis of antinociceptive action of χ-conotoxin AoIA at the noradrenaline transporter. [PDF]

Nat Struct Mol Biol
Belleza OJV, Zhang H, Schmidhammer H, Gonzalez TI, Ciotu CI, Tomašević N, Ocampo CMM, Fernando JC, Koehbach J, Schwarz P, Al Makhlouf M, Tajti G, Hasinger S, Kastner N, Avsar O, Retzl B, Jäntsch K, Jiang Y, Hellinger R, Fischer MJM, Rosengren KJ, Gruber CW, Villaraza AJL, Stockner T, Spetea M, Xu HE, Sitte HH.   +26 more
europepmc   +1 more source

From marine predator to pharmacology: Conotoxin diversity, discovery, and therapeutic potential. [PDF]

Zool Res
Mao KL, Fu JX, Chen J, Liao YL, Huang ML, Chen Z, Lin LM, Shi Q, Gao BM.   +8 more
europepmc   +1 more source

From neuropeptides to toxins: illuminating the origins of venom complexity in cone snails. [PDF]

Mol Biol Evol
Koch TL, Ferrari G, Sumanam SB, Salcedo PF, Watkins M, Chase K, Tooming-Klunderud A, Lluisma AO, Yanagihara A, Young ND, Olivera BM, Undheim EAB, Safavi-Hemami H.   +12 more
europepmc   +1 more source