CoQ10 for cardiovascular disease [PDF]
Pharmacy Today, 2016 lasted 1 year. Results were mixed, with little evidence from these trials to support or refute the value of CoQ10.3 The Q-SYMBIO trial, published in 2014 (not included in the Cochrane review), included 420 patients from nine different countries.4 The endpoints, assessed at 16 weeks, were change in New York Heart Association (NYHA) class, 6-minute walk ...
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Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline [PDF]
, 2010 Previous studies of the effects of coenzyme Q10 and minocycline on mouse models of Huntington’s disease have produced conflicting results regarding their efficacy in behavioral tests.
Allan J. Tobin +13 more
core +3 more sources
Production of CoQ10 in fission yeast by expression of genes responsible for CoQ10 biosynthesis
Bioscience, Biotechnology, and Biochemistry, 2015 Abstract Coenzyme Q10 (CoQ10) is essential for energy production and has become a popular supplement in recent years. In this study, CoQ10 productivity was improved in the fission yeast Schizosaccharomyces pombe. Ten CoQ biosynthetic genes were cloned and overexpressed in S. pombe. Strains expressing individual CoQ biosynthetic genes did
Daisuke, Moriyama +6 more
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Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]
, 2016 Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V +7 more
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Depletion and Supplementation of Coenzyme Q10 in Secondary Deficiency Disorders
Frontiers in Bioscience-Landmark, 2022 Coenzyme Q10 (CoQ10) deficiency is broadly divided into two types, primary and secondary. Primary CoQ10 deficiencies are relatively rare disorders resulting from mutations in genes directly involved in the CoQ10 biosynthetic pathway, and are not a ...
David Mantle +2 more
doaj +1 more source
Ubiquinol Reduces Muscle Wasting but Not Fatigue in Tumor-Bearing Mice [PDF]
, 2014 Purpose: Fatigue is the most common and distressing symptom reported by cancer patients during and after treatment. Tumor growth increases oxidative stress and cytokine production, which causes skeletal muscle wasting and cardiac dysfunction. The purpose
Clark, Yvonne +3 more
core +2 more sources
The Emerging Role of Disturbed CoQ Metabolism in Nonalcoholic Fatty Liver Disease Development and Progression [PDF]
, 2015 Although non-alcoholic fatty liver disease (NAFLD), characterised by the accumulation of triacylglycerol in the liver, is the most common liver disorder, the causes of its development and progression to the more serious non-alcoholic steatohepatitis ...
Elena Bravo +3 more
core +3 more sources
Acute and chronic effects of multivitamin/mineral supplementation on objective and subjective energy measures [PDF]
, 2020 Background: Vitamins and minerals play an essential role within many cellular processes including energy production and metabolism. Previously, supplementation with a multivitamin/mineral (MVM) for ≥28 days resulted in improvements to cognition and ...
Dodd, Fiona +7 more
core +2 more sources
RSC Advances, 2022 The new objective of sustainable analytical chemistry is to develop validated robust, swift, simple and highly sensitive analytical methods that are based on cost effective sensing technology.
Anam Naz Soomro +5 more
openaire +2 more sources
Coenzyme Q10 as a therapeutic candidate for treating inherited photoreceptor degeneration [PDF]
, 2017 Inherited photoreceptor degeneration (IPD): The human retina is a highly specialised tissue that enables the perception of light across a range of intensities and colours.
Biswas, Lincoln +5 more
core +4 more sources