Results 41 to 50 of about 728,641 (268)

The Multistationarity Structure of Networks with Intermediates and a Binomial Core Network [PDF]

Bulletin of Mathematical Biology, 2019
This work addresses whether a reaction network, taken with mass-action kinetics, is multistationary, that is, admits more than one positive steady state in some stoichiometric compatibility class. We build on previous work on the effect that removing or adding intermediates has on multistationarity, and also on methods to detect multistationarity for ...
AmirHosein Sadeghimanesh, Elisenda Feliu
openaire   +6 more sources

Mapping Childhood Cancer Care Services in Oceania: Methodological Lessons From the SIOP Global Mapping Programme

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The International Paediatric Oncology Society Global Mapping Programme aims to collect data on global paediatric oncology services by continent, with Africa and Latin America completed. This study reports on the methodology and lessons learned for Oceania, a unique continent with resource disparity across countries, multiple small island ...
Trisha Soosay Raj, Christy Noble, Amy Gray, Daniel C. Moreira, Jennifer Lowe, Maite Gorostegui, Gwenda Anga, Andrew Soma, Milena Lay Dos Santos, Siobhan Cross, Erin Luttrell, Michael Sullivan, Julie Cayrol, Julia Challinor, Neil Ranasinghe, Jordana McLoone, Claire E. Wakefield   +16 more
wiley   +1 more source

A Next-Generation Core Network Architecture for Mobile Networks [PDF]

Future Internet, 2019
Over the years, the cellular mobile network has evolved from a wireless plain telephone system to a very complex system providing telephone service, Internet connectivity and many interworking capabilities with other networks. Its air interface performance has increased drastically over time, leading to high throughput and low latency.
Forte A. G., Wang W., Veltri L., Ferrari G.   +3 more
openaire   +3 more sources

Co-targeting of VEGFR2 and PD-L1 promotes survival and vasculature normalization in pleural mesothelioma

OncoImmunology
Pleural mesothelioma (PM) is an aggressive cancer caused by asbestos exposure, with limited treatment options and poor prognosis, highlighting the need for more effective therapies.
Sophie Rovers, Jonas Van Audenaerde, Ruben Verloy, Jorrit De Waele, Louize Brants, Christophe Hermans, Ho Wa Lau, Céline Merlin, Maria Möller Ribas, Peter Ponsaerts, Steven Van Laere, Filip Lardon, An Wouters, Scott A. Fisher, Jan van Meerbeeck, Elly Marcq, Evelien Smits   +16 more
doaj   +1 more source

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer

Redox Biology, 2021
Auranofin (AF) is an FDA-approved antirheumatic drug with anticancer properties that acts as a thioredoxin reductase 1 (TrxR) inhibitor. The exact mechanisms through which AF targets cancer cells remain elusive.
Laurie Freire Boullosa, Jinthe Van Loenhout, Tal Flieswasser, Jorrit De Waele, Christophe Hermans, Hilde Lambrechts, Bart Cuypers, Kris Laukens, Esther Bartholomeus, Vasiliki Siozopoulou, Winnok H. De Vos, Marc Peeters, Evelien L.J. Smits, Christophe Deben   +13 more
doaj   +1 more source

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

Protein-level profiling of TIGIT axis components in human PDAC reveals immune–suppressive expression patterns

Cancer Immunology, Immunotherapy
Purpose In pancreatic ductal adenocarcinoma (PDAC), immune checkpoint inhibitors have shown limited efficacy, and the role of the TIGIT axis remains underexplored.
D. Quatannens, Y. Verhoeven, S. van der Heijden, D. Peeters, J. Claes, C. Hermans, H. Lambrechts, K. Zwaenepoel, P. van Dam, M. Peeters, H. Prenen, S. Koljenovic, J. De Waele, C. Faes, F. Lardon, G. Roeyen, E. Smits, J. Van Audenaerde   +17 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Discussion on the evolution of architecture of the core network of cellular Internet of things

Dianxin kexue, 2023
At present, there are two Internet of things networks facing 2G, 4G, NB-IoT and facing toB core networks.In order to simplify the network, enhance the capability, enhance the benefit, and facilitate the operation and maintenance, it is necessary to ...
Hongyuan MA, Wei ZHOU, Yan FU, Yongping SHAO, Dan LI   +4 more
doaj  

Research on lightweight 5GC application in emergency communication

Dianzi Jishu Yingyong, 2020
Emergency communication support requires rapid deployment, quick on-line and simplified configuration process, but the network architecture based on 3GPP standard is too large and complex to meet.
Zhu Xuetian, Wang Qiuhong, Zhang Shaowei, Hou Jijiang   +3 more
doaj   +1 more source