Results 61 to 70 of about 2,801,158 (293)

Research on lightweight 5GC application in emergency communication

Dianzi Jishu Yingyong, 2020
Emergency communication support requires rapid deployment, quick on-line and simplified configuration process, but the network architecture based on 3GPP standard is too large and complex to meet.
Zhu Xuetian, Wang Qiuhong, Zhang Shaowei, Hou Jijiang   +3 more
doaj   +1 more source

Critical dynamics of the k-core pruning process

, 2015
We present the theory of the k-core pruning process (progressive removal of nodes with degree less than k) in uncorrelated random networks. We derive exact equations describing this process and the evolution of the network structure, and solve them ...
Baxter, G. J., Dorogovtsev, S. N., Goltsev, A. V., Lee, K. -E., Mendes, J. F. F.   +4 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Centrality metrics and localization in core-periphery networks

, 2015
Two concepts of centrality have been defined in complex networks. The first considers the centrality of a node and many different metrics for it has been defined (e.g. eigenvector centrality, PageRank, non-backtracking centrality, etc).
Barucca, Paolo, Lillo, Fabrizio, Tantari, Daniele   +2 more
core   +1 more source

An Analysis and Enumeration of the Blockchain and Future Implications [PDF]

, 2020
The blockchain is a relatively new technology that has grown in interest and potential research since its inception. Blockchain technology is dominated by cryptocurrency in terms of usage.
LeBlanc, Nathanial
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

DRP1 depletion protects NK cells from hypoxia-induced dysfunction

Redox Report
Objectives The efficacy of cellular therapies has been disappointing in solid tumors. A major barrier that contributes to the low success rate, is hypoxia within the tumor microenvironment.
Tias Verhezen, Astrid Van Den Eynde, Peter Verstraelen, Laura Gehrcken, Gabriele Palmiotto, Ho Wa Lau, Winnok H. De Vos, Sanne Van Der Heijden, Louize Brants, Jöran Melis, Jonas Van Audenaerde, Felicia Rodrigues Fortes, Maxim Le Compte, Geert Roeyen, Hans Prenen, Diana Campillo-Davo, Eva Lion, Rafael J. Argüello, Steven Van Laere, Filip Lardon, Christophe Deben, An Wouters, Evelien Smits, Jorrit De Waele   +23 more
doaj   +1 more source

Oxidative Stress-Inducing Anticancer Therapies: Taking a Closer Look at Their Immunomodulating Effects

Antioxidants, 2020
Cancer cells are characterized by higher levels of reactive oxygen species (ROS) compared to normal cells as a result of an imbalance between oxidants and antioxidants.
Jinthe Van Loenhout, Marc Peeters, Annemie Bogaerts, Evelien Smits, Christophe Deben   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source