Results 211 to 220 of about 526,765 (304)

STING agonist-based ER-targeting molecules boost antigen cross-presentation. [PDF]

Nature
Wang X, Huang Z, Xing L, Shang L, Jiang J, Deng C, Yu W, Peng L, Yang H, Zheng X, Liu X, Yang H, Chen Y, Li Y, Liu J, Xie X, Xu W, Xia X, Liu Z, Liu W, Jiang S, Zeng Y, Lu L, Wang J.   +23 more
europepmc   +1 more source

Safety of Long-Acting Beta-Agonists in Children with Asthma [PDF]

, 2016
Bush, A, Frey, U
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Alkaline Adjuvant Regulates Proteolytic Activity of Macrophages for Antigen Cross-Presentation and Potentiates Radioimmunotherapy. [PDF]

Adv Mater
Li B, Tan Y, Lei JH, Deng M, Yu X, Wang X, Lei LM, He L, Deng CX, Dai Y.   +9 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Fungal immunization potentiates CD4⁺ T cell-independent cDC2 responses for cross-presentation. [PDF]

Front Immunol
Kulkarni NA, Nanjappa SG.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Matrix-M adjuvant triggers inflammasome activation and enables antigen cross-presentation through induction of lysosomal membrane permeabilization. [PDF]

NPJ Vaccines
Zarnegar B, Carow B, Eriksson J, Spennare E, Öhlund P, Akpinar E, Bringeland E, Osterman IL, Lundqvist L, Antti J, Handin N, Helgesson PH, Bankefors J, Lövgren Bengtsson K, Sellin ME, Palm AE, Stertman L, Lunderius Andersson C.   +17 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Shared pathway of WDFY4-dependent cross-presentation of immune complexes by cDC1 and cDC2. [PDF]

J Exp Med
Jo S, Ohara RA, Theisen DJ, Kim S, Liu T, Bullock CB, He M, Ou F, Chen J, Piersma SJ, Postoak JL, Yokoyama WM, Diamond MS, Murphy TL, Murphy KM.   +14 more
europepmc   +1 more source