Results 21 to 30 of about 530,471 (260)
Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides
Frontiers in Immunology, 2019 Human leukocyte antigen (HLA) alleles have a high degree of polymorphism, which determines their peptide-binding motifs and subsequent T-cell receptor recognition.
Shiyan Zhu +21 more
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In vitro Ag Cross-presentation and in vivo Ag Cross-presentation by Dendritic Cells in the Mouse [PDF]
BIO-PROTOCOL, 2012 Antigen cross presentation is important for effective immune responses to tumors and viral infections. Dendritic cells are professional antigen presenting cells and are unique in their ability to cross-present exogenous antigens on MHC class I molecules and activate antigen specific cytotoxic T cells.
Mallika Ghosh, Linda H Shapiro
openaire +3 more sources
Shaping of T Cell Functions by Trogocytosis
Cells, 2021 Trogocytosis is an active process whereby plasma membrane proteins are transferred from one cell to the other cell in a cell-cell contact-dependent manner.
Masafumi Nakayama +3 more
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Vaccines, 2023 This study found a higher percentage of CD8+ T cells in piglets immunized with a CVC1302-adjuvanted inactivated foot-and-mouth disease virus (FMDV) vaccine. We wondered whether the CVC1302-adjuvanted inactivated FMDV vaccine promoted cellular immunity by
Xiaoming Yu +11 more
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Sec61 in antigen cross-presentation
Oncotarget, 2015 Upon recognition of antigens in the peripheral tissue, dendritic cells (DCs) migrate toward the draining lymph node to present internalized and processed antigens on major histocompatibility complex (MHC) molecules to T cells. In a process termed cross-presentation, antigen-derived peptides are presented on MHC I molecules to cytotoxic T cells.
Matthias, Zehner, Sven, Burgdorf
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Oncolytic Immunotherapy: Dying the Right Way is a Key to Eliciting Potent Antitumor Immunity
Frontiers in Oncology, 2014 Oncolytic viruses (OVs) are novel immunotherapeutic agents whose anticancer effects come from both oncolysis and elicited antitumor immunity. OVs induce mostly immunogenic cancer cell death (ICD), including immunogenic apoptosis, necrosis/necroptosis ...
Zong Sheng eGuo +2 more
doaj +1 more source
Frontiers in Immunology, 2021 We have reported that tumor-derived autophagosomes (DRibbles) were efficient carriers of tumor antigens and DRibbles antigens could be present by DRibbles-activated B cells to stimulate effect and naïve T cells in mice. However, the effect of DRibbles on
Hongyan Ren +6 more
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Pharmaceutics, 2019 Explosive growth in nanotechnology has merged with vaccine development in the battle against diseases caused by bacterial or viral infections and malignant tumors.
Cheol Gyun Kim +2 more
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Frontiers in Immunology, 2018 Dendritic cells (DCs) are highly specialized antigen-presenting cells that bridge innate and adaptive immune responses in vertebrates, being key modulators in the initiation of specific responses.
Irene Soleto +3 more
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Frontiers in Immunology, 2018 Survivin is overexpressed in various types of human cancer, but rarely expressed in terminally differentiated adult tissues. Thus, survivin is a potential target antigen for a cancer vaccine.
Chen-Yi Chiang +8 more
doaj +1 more source