CSF Liquid Biopsy in High-Grade Gliomas: Identification of miRNA and Protein Biomarkers
Brain and SpineDr. Debora Giunti +11 more
doaj +2 more sources
GENE-41. LIQUID BIOPSY USING CELL FREE DNA FROM THE CEREBROSPINAL FLUID (CSF) IN GLIOMA [PDF]
Neuro-Oncology, 2018 Jun-Ichi Adachi +2 more
exaly +2 more sources
Tapping into the genome: the role of CSF ctDNA liquid biopsy in glioma
Neuro-Oncology Advances, 2022 Abstract Liquid biopsy has emerged as a novel noninvasive tool in cancer diagnostics. While significant strides have been made in other malignancies using liquid biopsy for diagnosis, disease monitoring, and treatment selection, development of these assays has been more challenging for brain tumors.
Friedman, Joshua S +3 more
openaire +2 more sources
Image_1_Comparison of the diagnostic value of liquid biopsy in leptomeningeal metastases: A systematic review and meta-analysis.jpeg [PDF]
, 2022 BackgroundBrain metastases (BM) include brain parenchymal (BPM) and leptomeningeal metastases (LM), which are associated with a poor prognosis and high mortality rate. Early and accurate diagnosis and timely, effective treatment are crucial for improving
Chunhui Li (501186) +4 more
core +1 more source
Frontiers in Oncology, 2021 We reported unique molecular features of cerebrospinal fluid (CSF) of nonsmall cell lung cancer (NSCLC) patients with leptomeningeal metastasis (LM), suggesting establishing CSF as a better liquid biopsy in clinical practices.
Yongsheng Wang +14 more
doaj +1 more source
Image_3_Comparison of the diagnostic value of liquid biopsy in leptomeningeal metastases: A systematic review and meta-analysis.jpeg [PDF]
, 2022 BackgroundBrain metastases (BM) include brain parenchymal (BPM) and leptomeningeal metastases (LM), which are associated with a poor prognosis and high mortality rate. Early and accurate diagnosis and timely, effective treatment are crucial for improving
Chunhui Li (501186) +4 more
core +1 more source
Image_2_Comparison of the diagnostic value of liquid biopsy in leptomeningeal metastases: A systematic review and meta-analysis.jpeg [PDF]
, 2022 BackgroundBrain metastases (BM) include brain parenchymal (BPM) and leptomeningeal metastases (LM), which are associated with a poor prognosis and high mortality rate. Early and accurate diagnosis and timely, effective treatment are crucial for improving
Chunhui Li (501186) +4 more
core +1 more source
Frontiers in Bioscience-Landmark, 2021 The molecular profiling of tumors is fundamental in the management of advanced non-small-cell lung cancer (NSCLC). A tissue specimen obtained from biopsy is needed for diagnosis and mutation analysis. However, this may not be feasible for some metastatic
Chi-Lu Chiang +3 more
doaj +1 more source
OS1.4 Liquid biopsy of the CSF in a series of GBM patients: preliminary results [PDF]
Neuro-Oncology, 2019 Abstract BACKGROUND Liquid biopsy (LB) by cerebrospinal fluid (CSF) can be useful to identify circulating tumour DNA (ctDNA), thus offering information about the heterogeneity of the neoplastic genome.
R Rudà +9 more
openaire +1 more source
Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation [PDF]
, 2023 Purpose: Current glioma diagnostic guidelines call for molecular profiling to stratify patients into prognostic and treatment sub-groups. In case the tumor tissue is inaccessible, cerebrospinal fluid (CSF) has been proposed as a reliable tumor DNA source
Santoro A. +20 more
core +1 more source