Results 31 to 40 of about 10,378 (206)
ctDNA-Based Liquid Biopsy of Cerebrospinal Fluid in Brain Cancer [PDF]
, 2021 Càncer de cervell; ADN tumoral circulant; Biòpsies líquidesCáncer de cerebro; ADN tumoral circulante; Biopsias liquidasBrain cancer; Circulating tumour DNA; Liquid biopsiesThe correct characterisation of central nervous system (CNS) malignancies is ...
Seoane Suarez, Joan +7 more
core +1 more source
Beyond the Blood: CSF-Derived cfDNA for Diagnosis and Characterization of CNS Tumors
Frontiers in Cell and Developmental Biology, 2020 Genetic data are rapidly becoming part of tumor classification and are integral to prognosis and predicting response to therapy. Current molecular tumor profiling relies heavily on tissue resection or biopsy. Tissue profiling has several disadvantages in
Abbye E. McEwen +8 more
doaj +1 more source
Cerebrospinal Fluid biomarkers in pediatric brain tumors: A systematic review
Neoplasia: An International Journal for Oncology Research, 2023 Central nervous system (CNS) tumors are the leading cause of cancer death in pediatric patients. Though these tumors typically require invasive surgical procedures to diagnose, cerebrospinal fluid (CSF) liquid biopsy presents a potential method for rapid
Kurt R. Lehner +4 more
doaj +1 more source
Genome-wide methylation analysis of circulating tumor DNA: A new biomarker for recurrent glioblastom
Heliyon, 2023 Background: Glioblastoma (GBM) is a malignant tumor with a short survival and poor prognosis and a lack of clinically validated biomarkers for diagnosis and prognosis.
Lin Dai, Zhihui Liu, Yi Zhu, Lixin Ma
doaj +1 more source
Neopterin level can be measured by intraocular liquid biopsy [PDF]
, 2023 International audienceRobust intraocular markers are needed in clinical practice for several inflammatory ophthalmological conditions in addition to advanced imaging, histology and immunohistochemistry tests in order to assure reliable diagnosis ...
Jullian, Eric +5 more
core +1 more source
Cerebrospinal fluid circulating tumor DNA depicts profiling of brain metastasis in NSCLC
Molecular Oncology, 2023 Brain metastasis (BM) genetically diverges from the primary tumor in non‐small‐cell lung cancer (NSCLC). Hence, accurately capturing clinically relevant alterations is pivotal for the delivery of targeted therapies.
Jun Wu +9 more
doaj +1 more source
Proof-of-Concept for Liquid Biopsy Disease Monitoring of MYC-Amplified Group 3 Medulloblastoma by Droplet Digital PCR [PDF]
, 2023 Background: Liquid biopsy diagnostic methods are an emerging complementary tool to imaging and pathology techniques across various cancer types. However, there is still no established method for the detection of molecular alterations and disease ...
Christian Dorfer +19 more
core +1 more source
Adding Value to Liquid Biopsy for Brain Tumors: The Role of Imaging [PDF]
, 2023 Clinical management in neuro-oncology has changed to an integrative approach that incorporates molecular profiles alongside histopathology and imaging findings.
Sina Bagheri +17 more
core +1 more source
Liquid biopsy and glioblastoma
Exploration of Targeted Anti-tumor Therapy, 2023 Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved.
Robert H. Eibl, Markus Schneemann
doaj +1 more source
BMC Cancer, 2019 Background Leptomeningeal metastasis (LM) is a predominantly late stage, devastating complication of a variety of malignant solid tumors. Diagnosis relies predominantly on neurological, radiographic, and cerebrospinal fluid (CSF) assessments.
Ann-Kathrin Stoppek +13 more
doaj +1 more source