HSP90AA1 interacts with CSFV NS5A protein and regulates CSFV replication via the JAK/STAT and NF-κB signaling pathway [PDF]
Frontiers in Immunology, 2022 Classical swine fever (CSF), caused by the classical swine fever virus (CSFV), is a highly contagious and fatal viral disease, posing a significant threat to the swine industry.
Chenchen Liu +30 more
doaj +5 more sources
RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome [PDF]
Virulence, 2022 Classical swine fever virus (CSFV), the etiological agent of classical swine fever (CSF), causes serious financial losses to the pig industry. Using yeast two-hybrid screening, we have previously identified ribosomal protein RPLP1 as a potential binding ...
Longxiang Zhang +5 more
doaj +3 more sources
Identification of E2 with improved secretion and immunogenicity against CSFV in piglets [PDF]
BMC Microbiology, 2020 Background Outbreaks of Classical swine fever virus (CSFV) cause significant economic losses in the swine industry. Vaccination is the major method to prevent and control the disease.
Huiling Xu +4 more
doaj +5 more sources
Porcine Viperin protein inhibits the replication of classical swine fever virus (CSFV) in vitro [PDF]
Virology Journal, 2017 Background Classical swine fever virus (CSFV) is the causative pathogen of Classical swine fever (CSF), a highly contagious disease of swine. Viperin is one of the hundreds of interferon-stimulated genes (ISGs), and possesses a wide range of antiviral ...
Wenliang Li +9 more
doaj +3 more sources
AIF1 was identified as an up-regulated gene contributing to CSFV Shimen infection in porcine alveolar macrophage 3D4/21 cells [PDF]
PeerJ, 2020 Classical swine fever (CSF) is a disease that is characterized by diffuse hemorrhaging, high fever, and high mortality rates. The pro-inflammatory characteristics of allograft inflammatory factor 1 (AIF1) have been well documented; however, insufficient ...
Xiaocheng Gong +8 more
doaj +4 more sources
Rab27a-mediated exosome secretion facilitates classical swine fever virus release and immune evasion [PDF]
Journal of VirologyClassical swine fever is a highly contagious disease caused by the classical swine fever virus (CSFV), a member of the Flaviviridae family. Exosomes are extracellular vesicles that mediate intercellular communication by transferring membrane components ...
Ning Li +7 more
doaj +2 more sources
COP I vesicles facilitate classical swine fever virus proliferation by transporting fatty acid synthase from the Golgi apparatus to the endoplasmic reticulum [PDF]
Journal of VirologyClassical swine fever virus (CSFV) is an enveloped, positive-sense, single-stranded RNA virus in the Flaviviridae family that remodels the cell’s endomembrane for its own propagation.
Liang Zhang +8 more
doaj +2 more sources
Creation of functional viruses from non-functional cDNA clones obtained from an RNA virus population by the use of ancestral reconstruction [PDF]
, 2015 RNA viruses have the highest known mutation rates. Consequently it is likely that a high proportion of individual RNA virus genomes, isolated from an infected host, will contain lethal mutations and be non-functional. This is problematic if the aim is to
Beer, Martin +7 more
core +32 more sources
Correction for Zhao et al., "IDO1 promotes CSFV replication by mediating tryptophan metabolism to inhibit NF-κB signaling". [PDF]
J VirolZhao F +19 more
europepmc +2 more sources
Classical swine fever virus recruits ALIX and ESCRT-III to facilitate viral budding [PDF]
mBioClassical swine fever virus (CSFV) incurs substantial economic losses in the global swine industry due to its persistent emergence and re-emergence across various countries.
Jinxia Chen +9 more
doaj +2 more sources