Results 31 to 40 of about 76,809 (334)

Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. [PDF]

open access: yes, 2018
Integrin activation regulates adhesion, extracellular matrix assembly, and cell migration, thereby playing an indispensable role in development and in many pathological processes.
Fan, Zhichao   +5 more
core   +2 more sources

Dysregulation of DPP4-CXCL12 Balance by TGF-β1/SMAD Pathway Promotes CXCR4+ Inflammatory Cell Infiltration in Keloid Scars

open access: yesJournal of Inflammation Research, 2021
ZongAn Chen,1,* Zhen Gao,1,* LingLing Xia,1 XiaoQing Wang,2,* LiMing Lu,3,* XiaoLi Wu1,* 1Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai ...
Chen Z, Gao Z, Xia L, Wang X, Lu L, Wu X
doaj  

T lymphocytes migrate upstream after completing the leukocyte adhesion cascade

open access: yesCell Adhesion & Migration, 2019
The leukocyte adhesion cascade is of critical importance for both the maintenance of immune homeostasis and the ability of immune cells to perform effector functions.
Nicholas R. Anderson   +2 more
doaj   +1 more source

MiR-886-3p down regulates CXCL12 (SDF1) expression in human marrow stromal cells. [PDF]

open access: yesPLoS ONE, 2010
Stromal Derived Factor 1 (SDF1 or CXCL12), is a chemokine known to be critical for the migration of cells in several tissue systems including the homing of the hematopoietic stem cell (HSC) to its niche in the bone marrow. A comparative analysis of miRNA
Manoj M Pillai   +4 more
doaj   +1 more source

Comparative study of CXC chemokines modulation in brown trout (Salmo trutta) following infection with a bacterial or viral pathogen [PDF]

open access: yes, 2017
Acknowledgements We would like to acknowledge Richard Paley, Tom Hill and Georgina Rimmer for their collaboration during brown trout infection challenges in CEFAS-Weymouth biosecurity facilities. Bartolomeo Gorgoglione, Stephen W. Feist and Nick G.
Feist, Stephen W.   +5 more
core   +1 more source

CXCL12/SDF-1 and CXCR4 [PDF]

open access: yesFrontiers in Immunology, 2015
Chemokines are a large family of structurally related chemoattractive cytokines, which have four conserved cysteines forming two disulfide bonds, and act through seven-transmembrane-spanning receptors coupled to heterotrimeric GTP-binding proteins (G-protein-coupled receptors).
openaire   +3 more sources

The clinical usefulness of chemokine C-X-C Motif Ligand 12 as a diagnostic marker for Papillary Thyroid Carcinoma

open access: yesIndian Journal of Pathology and Microbiology, 2020
Background: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer worldwide. It is essential to develop methods for the accurate diagnosis of PTC to avoid unnecessary surgery.
Sang Ah Lee   +4 more
doaj   +1 more source

Effects of cognate, non-cognate and synthetic CXCR4 and ACKR3 ligands on human lung endothelial cell barrier function. [PDF]

open access: yesPLoS ONE, 2017
Recent evidence suggests that chemokine CXCL12, the cognate agonist of chemokine receptors CXCR4 and ACKR3, reduces thrombin-mediated impairment of endothelial barrier function.
You-Hong Cheng   +4 more
doaj   +1 more source

The nuclear-cytoplasmic trafficking of a chromatin-modifyng and remodelling protein (KMT2C), in osteosarcoma [PDF]

open access: yes, 2018
Osteosarcoma is the most common paediatric primary non-hematopoietic bone tumor; the survival is related to the response to chemotherapy and development of metastases.
Carletti, Raffaella   +5 more
core   +1 more source

Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness

open access: yesOncoImmunology, 2018
The tumor microenvironment harbors cancer-associated fibroblasts that function as major modulators of cancer progression. Here, we assessed to which extent distinct cancer-associated fibroblast subsets impact mammary carcinoma growth and cancer cell ...
Maximilian Boesch   +10 more
doaj   +1 more source

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