Results 41 to 50 of about 76,809 (334)
Pharmaceuticals, 2020 CXC chemokine receptor 7 (CXCR7) is a G-protein-coupled receptor that signals through the β-arrestin pathway. Its ligands include interferon-inducible T cell α chemoattractant (CXCL11) and stromal cell-derived factor-1 (CXCL12).
Nicole Lounsbury
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Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2022 Introduction: Patients with diabetes are prone to develop complications related to the retina. So far, several genes have been reported in connection with the progression of retinopathy, and a group of these genes is genes involved in angiogenesis ...
Saba Gharibi +6 more
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The CXCL12/CXCR7 signaling axis, isoforms, circadian rhythms, and tumor cellular composition dictate gradients in tissue. [PDF]
PLoS ONE, 2017 Chemokine CXCL12 gradients drive chemotaxis in a CXCR4-dependent mechanism and have been implicated in cancer metastasis. While CXCL12 gradients are typically studied in organized, defined environments, the tumor microenvironment is disorganized. In vivo,
Phillip C Spinosa +3 more
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Function of chemokine (CXC motif) ligand 12 in periodontal ligament fibroblasts. [PDF]
PLoS ONE, 2014 The periodontal ligament (PDL) is one of the connective tissues located between the tooth and bone. It is characterized by rapid turnover. Periodontal ligament fibroblasts (PDLFs) play major roles in the rapid turnover of the PDL.
Yuichi Yashiro +5 more
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Frontiers in Neuroscience, 2023 BackgroundC-X-C motif chemokine 12 (CXCL12) is a chemokine that performs many functions. Studies have shown that CXCL12 can aggravate inflammatory symptoms in the central nervous system (CNS). Evidence also indicates that CXCL12 can promote the repair of
Dahe Lin +13 more
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PARP-1 and YY1 are important novel regulators of CXCL12 gene transcription in rat pancreatic beta cells. [PDF]
PLoS ONE, 2013 Despite significant progress, the molecular mechanisms responsible for pancreatic beta cell depletion and development of diabetes remain poorly defined. At present, there is no preventive measure against diabetes. The positive impact of CXCL12 expression
Jelena Marković +9 more
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Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
, 2010 Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana +9 more
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CXCR4, CXCL12 and the relative CXCL12-CXCR4 expression as prognostic factors in colon cancer
Tumor Biology, 2015 The CXCL12-CXCR4 axis is proposed to mediate metastasis formation. In this study, we examined CXCL12, CXCR4 and the relative CXCL12-CXCR4 expression as prognostic factors in two cohorts of colon cancer patients. Immunohistochemistry (IHC) and in situ hybridization (ISH) were used to study CXCR4, CXCL12 and relative CXCL12-CXCR4 expression in tissue ...
Luka, Stanisavljević +5 more
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CXCL12 (SDF-1)/CXCR4 Pathway in Cancer [PDF]
Clinical Cancer Research, 2010 Abstract Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane receptors, are major regulators of cell trafficking and adhesion. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; CD184).
Beverly A, Teicher, Simon P, Fricker
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NLRP3 Regulated CXCL12 Expression in Acute Neutrophilic Lung Injury
Journal of Inflammation Research, 2020 Yanwen Peng,1 Qiongli Wu,2 Hao Tang,3 Jingrou Chen,1 Qili Wu,1 Xiaofeng Yuan,4 Shiqiu Xiong,5 Yujin Ye,6 Haijin Lv7 1The Biotherapy Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, People’s Republic of China ...
Peng Y +8 more
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