Results 101 to 110 of about 10,559 (201)
High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma
Background Chemokines and their receptors are known to play important roles in the tumorigenesis of many malignancies. The aim of this study was to evaluate the prognostic impact of the expression of the chemokine SDF-1 and its receptors CXCR4 and CXCR7 ...
Wang Linhui +7 more
doaj +1 more source
The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone
scRNA‐seq analysis reveals age‐related changes in bone mesenchymal cells in male and female mice. Moreover, the comparison of aging and autophagy deficiency in bone mesenchymal cells shows overlap and suggests that age‐related decline in autophagy contributes to skeletal aging.
Melda Onal +12 more
wiley +1 more source
Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12. [PDF]
Although chemokines are well established to function in immunity and endothelial cell activation and proliferation, a rapidly growing literature suggests that CXC Chemokine receptors CXCR3, CXCR4 and CXCR7 are critical in the development and progression ...
Arya, R.K. +7 more
core +1 more source
The CXCR4/CXCL12 axis has been extensively associated with different types of cancer correlating with higher aggressiveness and metastasis. In diffuse large B-cell lymphoma (DLBCL), the expression of the chemokine receptor CXCR4 is involved in the ...
María José Moreno +14 more
doaj +1 more source
グリオブラストーマ細胞の増殖に対するヒト間葉系幹細胞の作用機構解明 [PDF]
筑波大学University of Tsukuba博士(医学)Doctor of Philosophy in Medical Sciences2012【要旨 ...
106106, 秋本, 恵子
core +1 more source
Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...
Duan, Zhenfeng +5 more
core +3 more sources
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang +13 more
wiley +1 more source
CXCR7 mediates angiogenesis in human glioma
64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Guentchev, M +3 more
openaire +1 more source
The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells
Background Migration of metastatic tumor cells from the bloodstream into lymph nodes is thought to be facilitated by expression of the chemokine receptors CCR7, CXCR4 and, for B cell-derived tumors, CXCR5. Expression of their respective chemokine ligands
Jaén Juan C +4 more
doaj +1 more source
The early stages of heart development: insights from chicken embryos [PDF]
The heart is the first functioning organ in the developing embryo and the detailed understanding of the molecular and cellular mechanisms involved in its formation provides insights into congenital malformations affecting its function and therefore the ...
Alsan +19 more
core +2 more sources

