Results 71 to 80 of about 1,935 (206)

Analysis on the internal exposure levels of five food additives in primary and secondary school students in Beijing City

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo investigate the internal exposure levels of urinary five food additives among primary and secondary school students in Beijing.MethodsIn September 2016, 900 urine samples were collected from children and adolescents in primary and secondary ...
XU Xin, NIU Yumin, SHAO Bing
doaj   +1 more source

The carbonic anhydrase enzymes as new targets for the management of neglected tropical diseases

open access: yesArchiv der Pharmazie, Volume 358, Issue 1, January 2025.
The scientific literature dealing with the identification and development of selective inhibitors of the carbonic anhydrases expressed by the protozoans Trypanosoma cruzi (T. cruzi) and Leishmania spp. is reviewed and analyzed, with the aim to sustain the validation process of new classes of drugs useful for the management of neglected tropical ...
Gioele Renzi   +3 more
wiley   +1 more source

A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Trypanosoma cruzi carbonic anhydrase (TcCA) has recently emerged as an interesting target for the design of new compounds to treat Chagas disease. In this study we report the results of a structure-based virtual screening campaign to identify novel and ...
Manuel A. Llanos   +10 more
doaj   +1 more source

Direct HPLC-UV determination of cyclamate, saccharine and aspartame from soft drinks

open access: yes
Artificial sweeteners were introduced in therapy as sugar substitutes for diabetic patients. Nowadays these substances are widely used for sugar substitution in low calorie drinks and sweets. Most commonly used products to date are saccharine, cyclamate,
Balogh, C.   +4 more
core   +1 more source

A Toxicity Method with Calcium Cyclamate for Chronic Carcinogenesis Experiments

open access: yes, 1972
An experimental approach for determining the maximum tolerated dose of chemicals administered continuously or repeatedly ad libitum for the lifespan of animals is described.
Bela Toth
core   +1 more source

The choice of intense sweetener in the composition of medicated chewing gum under development

open access: yesФармацевтичний журнал, 2019
Considering the simplicity and ease of use, in recent years, more and more attention deserves medicated chewing gum (MCG), which plays the role of oral drug delivery system.
Yu. S. Maslii   +2 more
doaj   +1 more source

Use of two artificial sweeteners, cyclamate and acesulfame, to identify and quantify wastewater contributions in a karst spring

open access: yes, 2016
The identification and differentiation of different sources of contamination are crucial aspects of risk assessment in water resource protection. This is especially challenging in karst environments due to their highly heterogeneous flow fields.
Zirlewagen, Johannes   +4 more
core   +1 more source

Bitterness suppression with zinc sulfate and Na-cyclamate: A model of combined peripheral and central neural approaches to flavor modification

open access: yes, 2005
PURPOSE - Zinc sulfate is known to inhibit the bitterness of the antimalarial agent quinine [R. S. J. Keast. The effect of zinc on human taste perception. J. Food Sci. 68:1871-1877 (2003)].
Russell Keast (606795)   +1 more
core   +1 more source

Flow injection spectrophotometric determination of cyclamate in commercial products

open access: yes
O ciclamato (ácido ciclohexenossulfâmico e seus sais de sódio e cálcio) é um adoçante artificial utilizado em diversos produtos dietéticos pelas indústrias nacionais.
Gouveia, Sandro Thomaz
core   +1 more source

Genomic resolution of bacterial populations in saccharin and cyclamate degradation

open access: yes, 2019
The benefits of extensive artificial sweeteners use come at a cost of their ubiquitous occurrence in the aquatic environment. Biodegradation is crucial for the removal of artificial sweeteners in the environment, yet comprehensive characterizations of ...
Zhang, T   +5 more
core   +1 more source

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