Results 201 to 210 of about 72,449 (334)

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

Evidence that cyclic gmp regulates myosin interaction with the cytoskeleton during chemotaxis of Dictyostelium [PDF]

, 1988
Gang Liu, Peter C. Newell
openalex   +1 more source

Cyclic GMP-AMP Synthase (cGAS) Deletion Promotes Less Prominent Inflammatory Macrophages and Sepsis Severity in Catheter-Induced Infection and LPS Injection Models. [PDF]

Int J Mol Sci
Suksamai C, Kaewduangduen W, Phuengmaung P, Sae-Khow K, Charoensappakit A, Udomkarnjananun S, Lotinun S, Kueanjinda P, Leelahavanichkul A.   +8 more
europepmc   +1 more source

The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8⁺ T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer. [PDF]

Cancers (Basel), 2023
Nakajima S, Kaneta A, Okayama H, Saito K, Kikuchi T, Endo E, Matsumoto T, Fukai S, Sakuma M, Sato T, Mimura K, Saito M, Saze Z, Sakamoto W, Onozawa H, Momma T, Kono K.   +16 more
europepmc   +1 more source

Cyclic 3′,5′-GMP Independent Protein Kinase at the Outer Surface of Intact Ehrlich Cells

, 1977
Gunnar Ronquist, Gunnar Ågren, Sten Eklund, Christer Wernstedt   +3 more
openalex   +2 more sources

EFFECTS OF CYCLIC AMP‐ AND CYCLIC GMP‐PHOSPHODIESTERASE INHIBITORS ON IMMUNOLOGICAL RELEASE OF HISTAMINE AND ON LUNG CONTRACTION [PDF]

, 1981
Nelly Frossard, Yves Landry, G. Pauli, M. Ruckstuhl   +3 more
openalex   +1 more source

Extrachromosomal Circular DNA: Emerging Insights Into Cardiovascular Disease Mechanisms and Biomarker Potential

iLABMED, EarlyView.
Extrachromosomal circular DNA (eccDNA) has quite recently turned out to be a cardinal component in cardiovascular diseases (CVD), governing the gene expression and mechanisms of disease causation. Studies indicated an upregulation of eccDNA in pulmonary arterial hypertension (PAH), which makes it strikingly potential as a sensitive and specific ...
Saim Mahmood Khan, Jawairya Muhammad Hussain, Surraiya Riaz Mahmood Khan, Bushra Nadeem, Tahniyat Naseem, Hammad Jawed, Aina Lashari   +6 more
wiley   +1 more source

The regulatory mechanism of cyclic GMP-AMP synthase on inflammatory senescence of nucleus pulposus cell. [PDF]

J Orthop Surg Res
Sun R, Wang F, Zhong C, Shi H, Peng X, Gao JW, Wu XT.   +6 more
europepmc   +1 more source

A Therapeutic Vaccine in Combination with Cyclic GMP-AMP Cures More Differentiated Melanomas in Mice. [PDF]

J Immunol, 2023
Alam MM, Gower T, Jiang M, Oppenheim JJ, Yang.   +4 more
europepmc   +1 more source

The Action of Dibutyryl Cyclic GMP (N2-2’-O-Dibutyryl Cyclic Guanosine-3’, 5’-Mono-Phosphate) on the Ileum of Guinea Pig

, 1973
Issei Takayanagi, Keijiro Takagi
openalex   +1 more source