Results 231 to 240 of about 40,137 (294)
Molecular Microbiology, EarlyView.ABSTRACT BosR is a novel nucleic acid‐binding protein in the ferric uptake regulator (FUR) family that regulates gene expression in the Lyme disease spirochete Borrelia (Borreliella) burgdorferi. This issue of Molecular Microbiology contains a comprehensive transcriptomic study that keenly defines the regulatory swath of BosR in the vertebrate host of ...
D. Scott Samuels, Meghan C. Lybecker
wiley +1 more source
Mitochondrial (mt)DNA-cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling promotes pyroptosis of macrophages via interferon regulatory factor (IRF)7/IRF3 activation to aggravate lung injury during severe acute pancreatitis. [PDF]
Cell Mol Biol LettPeng Y +8 more
europepmc +1 more source
Molecular Oral Microbiology, EarlyView.We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
M. Paula Goetting‐Minesky +8 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT In bread wheat (Triticum aestivum L.), cysteine (Cys) residues within the N‐ and C‐termini of high‐molecular‐weight glutenin subunits (HMW‐GSs) critically influence dough quality. However, the functional significance of Cys residue in their central repeat domain (CRD) remains unclear.
Bo Wei +16 more
wiley +1 more source
The therapeutic role of exercise training during menopause for reducing vascular disease
Experimental Physiology, EarlyView.Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing +4 more
wiley +1 more source
Defense gene induction in tobacco by nitric oxide, cyclic GMP, and cyclic ADP-ribose
, 1998 Jörg Durner +2 more
openalex +2 more sources
Experimental Physiology, EarlyView.Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro +8 more
wiley +1 more source
Role of calcium in regulating the cyclic GMP cascade of phototransduction in retinal rods.
, 1986 Vincent Torre, H.R. Matthews, T.D. Lamb
openalex +2 more sources
Experimental Physiology, EarlyView.ABSTRACT Gastrointestinal conditions such as irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) are characterized by alterations in physiological and immune functions. Given the circadian clock influences gastrointestinal physiology and immunity, we hypothesized that the peripheral circadian clock is altered in these patients and ...
Sophie Fowler +12 more
wiley +1 more source