Results 21 to 30 of about 587,828 (75)

Mechanical deformation of monocytic THP-1 cells : occurrence of two seqential phases with differential sensitivity to metabolic inhibitors [PDF]

Experimental Biology Online - EBO 2 (1997) 5, 2007
Blood leukocytes can exhibit extensive morphological changes during their passage through small capillary vessels. The human monocytic THP-1 cell line was used to explore the metabolic dependence of these shape changes. Cells were aspirated into micropipettes for determination of the rate of protrusion formation.
arxiv  

The Efficacy of Cyclooxygenase-2 Inhibitors for the Male Treatment of Lower Urinary Tract Symptoms: A Systematic Review and Meta-Analysis. [PDF]

Am J Mens Health, 2023
Tang G, Liu M, Ding G, Liu S, Chu Y, Cui Y, Wu J.   +6 more
europepmc   +1 more source

Effects of Cyclooxygenase-2 Inhibitors on Gastrointestinal Malignancies: a Systematic Review and Meta-analysis. [PDF]

Indian J Surg Oncol, 2022
Jiang YX, Chen Y, Sun HH, Xu SC.
europepmc   +1 more source

Regulation of interferon production as a potential strategy for COVID-19 treatment [PDF]

arXiv, 2020
Regulating the upstream of the cytokines production could be a promising strategy to the treatment of COVID-19. We suggest to pay more attention to the dysregulated IFN-I production in COVID-19 and to considerate cGAS, ALK and STING as potential therapeutic targets preventing cytokine storm.
arxiv  

Novel Benzo[4,5]imidazo[1,2-a]pyrimidine derivatives as selective Cyclooxygenase-2 Inhibitors: Design, synthesis, docking studies, and biological evaluation. [PDF]

Med Chem Res, 2023
Bayanati M, Khoramjouy M, Faizi M, Movahed MA, Mahboubi-Rabbani M, Zarghi A.   +5 more
europepmc   +1 more source

Computational Analysis and Biological Activities of Oxyresveratrol Analogues, the Putative Cyclooxygenase-2 Inhibitors. [PDF]

Molecules, 2022
Jongkon N, Seaho B, Tayana N, Prateeptongkum S, Duangdee N, Jaiyong P.   +5 more
europepmc   +1 more source

Efficacy and safety of cyclooxygenase 2 inhibitors for desmoid tumor management: a systematic review. [PDF]

Nagoya J Med Sci, 2021
Emori M, Matsumoto Y, Murahashi Y, Yoshida M, Nishida Y.   +4 more
europepmc   +1 more source

A high-throughput analysis of ovarian cycle disruption by mixtures of aromatase inhibitors [PDF]

arXiv, 2016
Background: Combining computational toxicology with ExpoCast exposure estimates and ToxCast assay data gives us access to predictions of human health risks stemming from exposures to chemical mixtures. Objectives: To explore, through mathematical modeling and simulations, the size of potential effects of random mixtures of aromatase inhibitors on ...
arxiv  

Natural Cyclooxygenase-2 Inhibitors Synergize With Butyrate to Augment Chicken Host Defense Peptide Gene Expression. [PDF]

Front Immunol, 2022
Yang Q, Burkardt AC, Sunkara LT, Xiao K, Zhang G.   +4 more
europepmc   +1 more source

The highly selective cyclooxygenase-2 inhibitor DFU is neuroprotective when given several hours after transient cerebral ischemia in gerbils [PDF]

Brain Research 927(2): 212-215 (2002), 2007
Several studies suggest that cyclooxygenase-2 contributes to the delayed progression of ischemic brain damage. In this study we examined whether the highly selective cyclooxygenase-2 inhibitor DFU reduces neuronal damage when administered several hours after 5 min of transient forebrain ischemia in gerbils.
arxiv