Results 11 to 20 of about 31,837 (203)
Cyclophilins A, B, and C Role in Human T Lymphocytes Upon Inflammatory Conditions
Cyclophilins (Cyps) are a group of peptidyl-prolyl cis/trans isomerases that play crucial roles in regulatory mechanisms of cellular physiology and pathology in several inflammatory conditions.
Sandra Gegunde +8 more
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Objective To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia. Methods In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in ...
Samettin Celik, Canan Soyer Çalışkan
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Association of cyclophilins and cardiovascular risk factors in coronary artery disease
Cyclophilins are chaperone proteins that play important roles in signal transduction. Among them, cyclophilins A, B, C, and D were widely associated with inflammation and cardiovascular diseases. Cyclophilins A and C have been proposed as coronary artery
Sandra Gegunde +22 more
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In vitro studies suggest cyclosporine A derivatives could help treat coronaviruses such as SARS.
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Non‐Immunosuppressive Cyclophilin Inhibitors
AbstractCyclophilins, enzymes with peptidyl‐prolyl cis/trans isomerase activity, are relevant to a large variety of biological processes. The most abundant member of this enzyme family, cyclophilin A, is the cellular receptor of the immunosuppressive drug cyclosporine A (CsA).
Cordelia Schiene‐Fischer +2 more
openaire +4 more sources
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
The mitochondrial permeability transition pore is a nonspecific transmembrane channel. Inhibition of mitochondrial permeability transition pore opening has been shown to alleviate mitochondrial swelling, calcium overload, and axonal degeneration ...
Yang Yang +12 more
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Background New therapeutic drugs are urgently needed against visceral leishmaniasis because current drugs, such as pentavalent antimonials and miltefosine, produce severe side effects and development of resistance.
Zhi-Wan Zheng +8 more
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SIV replication in human cells
Current human immunodeficiency virus type 1 (HIV-1) pandemic is believed to originate from cross-species transmission of simian immunodeficiency virus (SIV) into human population.
Hiroaki eTakeuchi, Ryuta eSakuma
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We previously reported that cyclophilin A protein is up-regulated in cortical neuronal cultures following several preconditioning treatments. In the present study, we have demonstrated that adenoviral-mediated over-expression of cyclophilin A in rat ...
Sherif Boulos +5 more
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