Results 31 to 40 of about 45,384 (211)
Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State [PDF]
, 2016 The mitochondrial thioredoxin system (NADPH, thioredoxin reductase, thioredoxin) is a major redox regulator. Here we have investigated the redox correlation between this system and the mitochondrial enzyme cyclophilin D.
Bindoli, Alberto +7 more
core +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
CypB promotes cell proliferation and metastasis in endometrial carcinoma
BMC Cancer, 2021 Background The molecular pathogenesis of endometrial cancer is not completely understood. CypB upregulated in many cancers, however, its role in endometrial carcinoma has not been studied.
Jing Liu +7 more
doaj +1 more source
Overexpression, purification, and characterization of yeast cyclophilins A and B [PDF]
Protein Science, 1992 AbstractTwo isoforms of yeast cyclophilins, yCyPA and yCyPB, have been subcloned, expressed in Escherichia coli, and purified to homogeneity. The full‐length (163‐amino acid) yeast CyPA was easily expressed and purified; however, only a genetically truncated, 186‐residue form of yCyPB lacking a putative 20‐amino acid signal sequence could be purified ...
L D, Zydowsky +4 more
openaire +2 more sources
The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer [PDF]
Proceedings of the National Academy of Sciences, 2002 The nuclear translocation of peptide hormones, such as the somatolactogenic hormone prolactin, after receptor internalization has been widely reported. Prolactin has been demonstrated to interact with cyclophilin B, a member of the immunophilin family of proteins.
Michael A, Rycyzyn, Charles V, Clevenger
openaire +2 more sources
Biotechnology & Biotechnological Equipment, 2019 The aim of this study was to investigate the effects of cyclophilin B on MC3T3-E1 cells and the underlying mechanism. CCK-8 assay was used to evaluate the cell activity, polymerase chain reaction to verify the overexpression of cyclophilin B, western ...
Fan Mei, Yanhong Tu
doaj +1 more source
BMC Research Notes, 2012 Background Hyperelastosis cutis is an inherited autosomal recessive connective tissue disorder. Affected horses are characterized by hyperextensible skin, scarring, and severe lesions along the back. The disorder is caused by a mutation in cyclophilin B.
Boudko Sergei P +5 more
doaj +1 more source
MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface
eLife, 2020 The type one interferon induced restriction factor Myxovirus resistance B (MxB) restricts HIV-1 nuclear entry evidenced by inhibition of 2-LTR but not linear forms of viral DNA.
Richard J Miles +5 more
doaj +1 more source
A vaccine to prevent initial loss of cognition and eventual Alzheimer's disease in elderly persons
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021 Prevention is better than cure and prevention of Alzheimer's disease (AD) may be possible. In elderly persons who are cognitively normal, synaptic hypometabolism as shown by reduced cerebral uptake of fluorodeoxyglucose (18F‐FDG), provides a premonitory ...
Jeffrey Fessel
doaj +1 more source
Cyclophilin B Expression in Renal Proximal Tubules of Hypertensive Rats [PDF]
Hypertension, 2000 Abstract —Rat cyclophilin-like protein (Cy-LP) is a candidate hypertension gene initially identified by differential hybridization and implicated in renal mechanisms of salt retention and high blood pressure. We report the molecular characterization of rat cyclophilin B (CypB) and demonstrate, through sequence analysis and
D B, Kainer, P A, Doris
openaire +2 more sources