Results 41 to 50 of about 45,384 (211)
PLoS ONE, 2021 Whitefly, Bemisia tabaci (Gennadius) is an important pest of cotton causing direct damage as sap feeder and vector of Cotton leaf curl virus (CLCuV). Previous few studies suggest that female whiteflies are more efficient vector of begomovirusthan males ...
Ikbalpreet Singh +4 more
doaj +1 more source
Cyclophilin-A is bound to through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex [PDF]
, 2004 Although cyclophilin A (CyP-A) is a relatively abundant small immunophilin present in the cytoplasm of all mammalian cells, its general function(s) in the absence of the immunosuppressant drug cyclosporin A is not known.
Galigniana, Mario Daniel +3 more
core +2 more sources
Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence. [PDF]
Proceedings of the National Academy of Sciences, 1991 We report the cloning and characterization of a cDNA encoding a second human cyclosporin A-binding protein (hCyPB). Homology analyses reveal that hCyPB is a member of the cyclophilin B (CyPB) family, which includes yeast CyPB, Drosophila nina A, and rat cyclophilin-like protein.
E R, Price +5 more
openaire +2 more sources
Identification of a non-mammalian leptin-like gene:characterization and expression in the tiger salamander (Ambystoma tigrinum) [PDF]
, 2006 Leptin is well established as a multifunctional cytokine in mammals. However, little is known about the evolution of the leptin gene in other vertebrates. A recently published set of ESTs from the tiger salamander (Ambystoma tigrinum) contains a sequence
Boswell, Timothy +5 more
core +1 more source
Receptor‐Mediated Transcytosis of Cyclophilin B Through the Blood—Brain Barrier [PDF]
Journal of Neurochemistry, 1999 Abstract: Cyclophilin B (CyPB) is a cyclosporin A (CsA)‐binding protein mainly located in intracellular vesicles and secreted in biological fluids. In previous works, we demonstrated that CyPB interacts with T lymphocytes and enhances in vitro cellular incorporation and activity of CsA.
Carpentier, Mathieu +8 more
openaire +3 more sources
Cyclosporine inhibits a direct interaction between cyclophilins and hepatitis C NS5A.
PLoS ONE, 2010 BackgroundHepatitis C Virus (HCV) infection is a leading indication for liver transplantation. HCV infection reoccurs almost universally post transplant, decreasing both graft longevity and patient survival.
Fiona Fernandes +2 more
doaj +1 more source
Alternative cell death pathways and cell metabolism [PDF]
, 2013 While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Fulda, Simone
core +2 more sources
SIV replication in human cells
Frontiers in Microbiology, 2012 Current human immunodeficiency virus type 1 (HIV-1) pandemic is believed to originate from cross-species transmission of simian immunodeficiency virus (SIV) into human population.
Hiroaki eTakeuchi, Ryuta eSakuma
doaj +1 more source
Structural and biochemical insights of CypA and AIF interaction [PDF]
, 2017 The Cyclophilin A (CypA)/Apoptosis Inducing Factor (AIF) complex is implicated in the DNA degradation in response to various cellular stress conditions, such as oxidative stress, cerebral hypoxia-ischemia and traumatic brain injury.
Caporale, Andrea +10 more
core +1 more source
Lack of Cyclophilin B in Osteogenesis Imperfecta with Normal Collagen Folding [PDF]
New England Journal of Medicine, 2010 Osteogenesis imperfecta is a heritable disorder that causes bone fragility. Mutations in type I collagen result in autosomal dominant osteogenesis imperfecta, whereas mutations in either of two components of the collagen prolyl 3-hydroxylation complex (cartilage-associated protein [CRTAP] and prolyl 3-hydroxylase 1 [P3H1]) cause autosomal recessive ...
Aileen M, Barnes +10 more
openaire +2 more sources