Results 51 to 60 of about 34,953 (257)
Interaction between maternal passive smoking during pregnancy and CYP1A1 and GSTs polymorphisms on spontaneous preterm delivery. [PDF]
PLoS ONE, 2012 OBJECTIVE: The present study aimed to examine the association between maternal passive smoking during pregnancy and the risk of spontaneous PTD and to explore the potential interaction of the single or joint gene polymorphism of CYP1A1 and GSTs with ...
Yi-Juan Luo +12 more
doaj +1 more source
International journal of pharmaceutics, 2019 The occurrence of lung cancer is linked with tobacco smoking, mainly through the generation of polycyclic aromatic hydrocarbons (PAHs). Elevated activity of cytochrome P4501A1 (CYP1A1) plays an important role in the metabolic processing of PAHs and its ...
Meng-Tian Zhang +8 more
semanticscholar +1 more source
Expression profiles of CYP1A1 and CYP1B1 enzymes in Non-small Cell Lung Cancer of Turkish Patients
Сибирский онкологический журналBackground. The cytochrome P450 enzymes CYP1A1 and CYP1B1 are involved in the metabolism of carcinogens and have been linked to various cancers, including lung cancer, primarily through their overexpression in tumor tissues. Aim of study.
H. Bayram +7 more
doaj +1 more source
Polymorphisms of CYP1A1, CYP1A2, CYP19, and SULT1A1 genes in women with early miscarriage
Фундаментальная и клиническая медицина, 2019 Aim. To determine the frequency of the polymorphisms within the genes encoding estrogen metabolism enzymes: CYP1A1 (rs4646903), CYP1A2 (rs762551), CYP19 (rs700519) and SULT1A1 (rs9282861) in women with early miscarriage.Materials and Methods.
I. N. Noskova +2 more
doaj +1 more source
Molecular Medicine Reports, 2017 There is an endemic cardiomyopathy currently occurring in China, termed, Keshan disease (KD). The authors previously compared mitochondrial-associated gene expression profiles of peripheral blood mononuclear cells (PBMCs) derived from KD patients and ...
B. Zhou +6 more
semanticscholar +1 more source
Food and Chemical Toxicology, 2018 The Western diet contributes to nonalcoholic fatty liver disease (NAFLD) pathogenesis. Benzo[a]pyrene (BaP), a prototypical environmental pollutant produced by combustion processes, is present in charcoal-grilled meat.
Shigeyuki Uno, D. Nebert, M. Makishima
semanticscholar +1 more source
Passive smoking, Cyp1A1 gene polymorphism and dysmenorrhea [PDF]
Reproductive Toxicology, 2007 This study investigated whether the association between passive smoking exposure and dysmenorrhea is modified by two susceptibility genes, CYP1A1MspI and CYP1A1HincII.This report includes 1645 (1124 no dysmenorrhea, 521 dysmenorrhea) nonsmoking and nondrinking newly wed female workers at Anqing, China between June 1997 and June 2000.
Hong, Liu +7 more
openaire +2 more sources
Acute styrene exposure induces hepatocellular injury and molecular stress responses in Oryzias celebensis: Evidence for a tropical sentinel species in ecotoxicological monitoring [PDF]
Veterinary WorldBackground and Aim: Plastic-derived monomers such as styrene are increasingly detected in tropical freshwater ecosystems at concentrations approaching 0.8 mg/L.
Amelia Ramadhani Anshar +5 more
doaj +1 more source
Antioxidants, 2021 We hypothesized that an interplay between aryl hydrocarbon receptor (AhR) and cysteine-related thiolome at the kidney cortex underlies the mechanisms of (mal)adaptation to chronic intermittent hypoxia (CIH), promoting arterial hypertension (HTN). Using a
Maria João Correia +11 more
doaj +1 more source
Racial differences in CYP1A1 genotype and function
Toxicology Letters, 1995 The cytochrome P450 1A1 (CYP1A1) gene may be of critical importance in determining individual cancer susceptibility to aromatic hydrocarbons such as those in tobacco smoke. We compared the frequencies of CYP1A1 haplotypes, and complete genotypes, taking into account polymorphisms at 3 sites, including an African-specific polymorphism.
E, Taioli +5 more
openaire +2 more sources