Results 31 to 40 of about 6,140 (99)

Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy

open access: yeseLife, 2023
Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell biology, but study of these organisms using light microscopy is often hindered by their small size.
Benjamin Liffner   +8 more
doaj   +1 more source

Aurora kinases orchestrate mitosis; who are the players?

open access: yesBiomolecular Concepts, 2010
The Aurora are a conserved family of serine/threonine kinases with essential functions in cell division. In mitosis, Aurora kinases are required for chromosome segregation, condensation and orientation in the metaphase plate, spindle assembly, and the ...
Molla Annie
doaj   +1 more source

The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis

open access: yeseLife, 2015
Cytokinesis requires activation of the GTPase RhoA. ECT-2, the exchange factor responsible for RhoA activation, is regulated to ensure spatiotemporal control of contractile ring assembly.
Donglei Zhang, Michael Glotzer
doaj   +1 more source

Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction

open access: yeseLife, 2016
Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown ...
Junqi Huang   +9 more
doaj   +1 more source

An ATM-CHK2-INCENP pathway prevents chromatin breakage by regulating the abscission checkpoint

open access: yesMolecular & Cellular Oncology, 2021
In response to chromatin bridges, the chromosomal passenger complex (CPC) delays completion of cytokinesis (abscission) to prevent chromosome breakage.
Eleni Petsalaki, George Zachos
doaj   +1 more source

Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments

open access: yeseLife, 2017
The actomyosin ring generates force to ingress the cytokinetic cleavage furrow in animal cells, yet its filament organization and the mechanism of contractility is not well understood.
Felix Spira   +8 more
doaj   +1 more source

A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis

open access: yesPlant Direct, 2023
Meiosis is a specialized cell division that halves the number of chromosomes in two consecutive rounds of chromosome segregation. In angiosperm plants is meiosis followed by mitotic divisions to form rudimentary haploid gametophytes.
Sorin Tanasa   +10 more
doaj   +1 more source

Regulation of the Total Cell Surface Area in Dividing Dictyostelium Cells

open access: yesFrontiers in Cell and Developmental Biology, 2020
When a cell divides into two daughter cells, the total cell surface area should increase. There are two models for membrane supply to support cell division: (1) unfolding of small surface membrane reservoirs such as microvilli or wrinkles and (2 ...
Masahito Tanaka   +2 more
doaj   +1 more source

Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis

open access: yesFrontiers in Genetics, 2020
The human Periodontal Ligament Stem Cells (hPDLSCs) exhibit self-renewal capacity and clonogenicity potential. The Extracellular Vesicles (EVs) secreted by hPDLSCs are particles containing lipids, proteins, mRNAs, and non-coding RNAs, among which ...
Luigi Chiricosta   +7 more
doaj   +1 more source

Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

open access: yesNeoplasia: An International Journal for Oncology Research, 2000
Survivin, a member of the inhibitor of apoptosis protein (IAP) family, is detected in most common human cancers but not in adjacent normal cells. Previous studies suggest that survivin associates with the mitotic spindle and directly inhibits caspase ...
Jun Chen   +11 more
doaj   +1 more source

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