Results 31 to 40 of about 390,147 (250)
Damage-associated molecular patterns in cancer: a double-edged sword [PDF]
Oncogene, 2016 Damage-associated molecular patterns (DAMPs) are released in response to cell death and stress, and are potent triggers of sterile inflammation. Recent evidence suggests that DAMPs may also have a key role in the development of cancer, as well as in the host response to cytotoxic anti-tumor therapy.
Hernandez, Celine +2 more
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Recognition of Elicitors in Grapevine: From MAMP and DAMP Perception to Induced Resistance
Frontiers in Plant Science, 2019 In a context of a sustainable viticulture, the implementation of innovative eco-friendly strategies, such as elicitor-triggered immunity, requires a deep knowledge of the molecular mechanisms underlying grapevine defense activation, from pathogen ...
Marie-Claire Héloir +16 more
doaj +1 more source
Changes of Damage Associated Molecular Patterns in COVID-19 Patients
Infectious Diseases & Immunity, 2021 Abstract Background: The development of severe coronavirus disease 2019 (COVID-19) is associated with systemic hyperinflammation, which drives multi-organ failure and death. Disease deterioration tends to occur when the virus is receding; however, whether other factors besides viral products are involved in the ...
Xing Fan +14 more
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Surgical trauma‐induced immunosuppression in cancer: Recent advances and the potential therapies
Clinical and Translational Medicine, 2020 Surgical resection remains the mainstay treatment for solid cancers, especially for localized disease. However, the postoperative immunosuppression provides a window for cancer cell proliferation and awakening dormant cancer cells, leading to rapid ...
Fan Tang +3 more
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Damage‐associated molecular patterns and coagulation
British Journal of HaematologyDamage‐associated molecular patterns (DAMPs), released into the extracellular space following tissue injury, are increasingly recognised as potent procoagulant molecules integral to haemostasis and the pathogenesis of thrombosis. Their procoagulant influence spans all phases of the cell‐based model of coagulation while simultaneously extending beyond ...
Jun Yong, Cheng‐Hock Toh
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Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells. [PDF]
PLoS ONE, 2012 Endogenous damage associated molecular pattern molecules (DAMPs) released from necrotic, damaged or stressed cells are associated with an inflammatory response.
Sebnem Unlu +7 more
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High mobility group box 1 (HMGB1) in COVID-19 [PDF]
Journal of Preventive Epidemiology, 2021 Fatemeh Kafi +3 more
doaj +1 more source
Frontiers in Immunology, 2018 Despite significant improvements in injury prevention and emergency response, injury-related death and morbidity continues to increase in the US and worldwide.
John Eppensteiner +4 more
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Neurobiology of Disease, 2013 Toll-like receptor 4 (TLR4) activation in neuron and astrocytes by High Mobility Group Box 1 (HMGB1) protein is a key mechanism of seizure generation. HMGB1 also activates the Receptor for Advanced Glycation Endproducts (RAGE), but it was unknown whether
Valentina Iori +11 more
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Plant–Plant Communication: Is There a Role for Volatile Damage-Associated Molecular Patterns? [PDF]
Frontiers in Plant Science, 2020 Damage-associated molecular patterns (DAMPs) are an ancient form of tissue-derived danger or alarm signals that initiate cellular signaling cascades, which often initiate defined defense responses. A DAMP can be any molecule that is usually not exposed to cells such as cell wall components, peptides, nucleic acid fragments, eATP and other compounds ...
Meents, A., Mithöfer, A.
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