Inflammation and damage-associated molecular patterns in major psychiatric disorders [PDF]
Trends in Psychiatry and Psychotherapy, 2023 Background Emerging evidence indicates that inflammation plays an important role as a mechanism underlying mental disorders. However, most of the research on inflammatory mechanisms focuses on serum levels of interleukins and very few studies have ...
Fernanda Endler Valiati +7 more
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Damage-associated molecular patterns in bacteraemic infection, including a comparative analysis with bacterial DNA, a pathogen-associated molecular pattern [PDF]
Scientific ReportsDamage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) are key triggers of inflammation in sepsis. However, they have rarely been studied simultaneously.
Helena Alpkvist +7 more
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The immune suppressive properties of damage associated molecular patterns in the setting of sterile traumatic injury [PDF]
Frontiers in Immunology, 2023 Associated with the development of hospital-acquired infections, major traumatic injury results in an immediate and persistent state of systemic immunosuppression, yet the underlying mechanisms are poorly understood.
Emily Horner +4 more
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Mitochondrial damage-associated molecular patterns: Neuroimmunomodulators in central nervous system pathophysiology [PDF]
Neural Regeneration ResearchNeuroinflammation contributes to a wide range of neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and multiple sclerosis.
Noah A. H. Brooks +2 more
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Damage-associated molecular patterns (DAMPs) in diseases: implications for therapy [PDF]
Molecular BiomedicineDamage-associated molecular patterns (DAMPs) are endogenous danger signal molecules released by damaged, stressed or dead cells that bind to pattern recognition receptors (PRRs), activating immune responses and inflammatory signaling pathways to play ...
Heya Lin +4 more
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Damage associated molecular patterns and neutrophil extracellular traps in acute pancreatitis [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Previous researches have emphasized a trypsin-centered theory of acute pancreatitis (AP) for more than a century. With additional studies into the pathogenesis of AP, new mechanisms have been explored.
Xiaoying Zhou +12 more
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Damage-Associated Molecular Patterns in Perioperative Anesthesia Care: A Clinical Perspective [PDF]
Anesthesia ResearchDamage-associated molecular patterns (DAMPs) are endogenous molecules released during cellular stress or injury that trigger sterile inflammation.
Wiriya Maisat, Koichi Yuki
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Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders [PDF]
Cells, 2022 Neuroinflammation is a common hallmark in different neurodegenerative conditions that share neuronal dysfunction and a progressive loss of a selectively vulnerable brain cell population.
Cláudia M. Deus +4 more
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Research progress on damage-associated molecular patterns in acute kidney injury [PDF]
Frontiers in ImmunologyAcute kidney injury (AKI) is a clinical syndrome characterized by a sudden dysfunction of the kidney, which is common worldwide, with a relatively high incidence and mortality rate.
Jiajia Li, Zhangxue Hu
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Preparation of mitochondrial damage-associated molecular patterns from mouse liver tissue [PDF]
STAR Protocols, 2022 Summary: Mitochondrial damage-associated molecular patterns (mitoDAMPs) are released from cells dying uncontrolled, non-apoptotic deaths, usually secondary to disease or trauma.
Lauren P. Westhaver +5 more
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