Results 21 to 30 of about 375,454 (242)
Damage-associated molecular patterns in trauma [PDF]
European Journal of Trauma and Emergency Surgery, 2019 AbstractIn 1994, the “danger model” argued that adaptive immune responses are driven rather by molecules released upon tissue damage than by the recognition of “strange” molecules. Thus, an alternative to the “self versus non-self recognition model” has been provided.
Relja, Borna, Land, Walter Gottlieb
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Curcumin induces immunogenic cell death in murine colorectal carcinoma CT26 cells
Pharmacological Research - Modern Chinese Medicine, 2022 Different stressors of the endoplasmic reticulum (ER) can trigger immunogenic cell death (ICD), a modality of regulated cell death that can be therapeutically used to induce antitumor immune responses. Curcumin has been pointed out as an ER stressor, but
Rayane Ganassin +7 more
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Mechanisms of Immunothrombosis by SARS-CoV-2
Biomolecules, 2021 SARS-CoV-2 contains certain molecules that are related to the presence of immunothrombosis. Here, we review the pathogen and damage-associated molecular patterns.
María Teresa Hernández-Huerta +12 more
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The Role of C-Type Lectin Receptor Signaling in the Intestinal Microbiota-Inflammation-Cancer Axis
Frontiers in Immunology, 2022 As a subset of pattern recognition receptors (PRRs), C-type lectin-like receptors (CLRs) are mainly expressed by myeloid cells as both transmembrane and soluble forms.
Muhan Li +7 more
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Frontiers in Plant Science, 2021 In response to herbivore attack, plants release large amounts of volatiles that can serve as attractants for the natural enemies of the attacking herbivores. Such responses are typically triggered by damage- and insect-associated factors.
Carla M. Arce +3 more
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Damage-Associated Molecular Patterns in Inflammatory Diseases [PDF]
Immune Network, 2018 Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that are released from damaged or dying cells and activate the innate immune system by interacting with pattern recognition receptors (PRRs). Although DAMPs contribute to the host's defense, they promote pathological inflammatory responses.
Roh, Jong Seong, Sohn, Dong Hyun
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Kawasaki Disease Following Severe Sunburn Injury
Frontiers in Pediatrics, 2020 Background: Although an etiology of Kawasaki disease (KD) is unknown, an aberrant innate immune system in predisposed individuals has been proposed to play a key role in the development of KD vasculitis.
Seigo Okada +7 more
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Danger signals in traumatic hemorrhagic shock and new lines for clinical applications
Frontiers in Physiology, 2023 Hemorrhage is the leading cause of death in severe trauma injuries. When organs or tissues are subjected to prolonged hypoxia, danger signals—known as damage-associated molecular patterns (DAMPs)—are released into the intercellular environment.
Frédérique Dufour-Gaume +3 more
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Biomedicines, 2022 Mitochondrial DNA (mtDNA) has been identified as a biomarker for predicting sepsis mortality. Although preclinical studies suggested that necroptosis could explain the mechanistic link of mtDNA in sepsis, this is not yet evident in patients with sepsis ...
Hayoung Choi +4 more
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DAMPs and alarmin gene expression patterns in aging healthy and diseased mucosal tissues
Frontiers in Oral Health, 2023 IntroductionPeriodontitis is delineated by a dysbiotic microbiome at sites of lesions accompanied by a dysregulated persistent inflammatory response that undermines the integrity of the periodontium.
O. A. Gonzalez +2 more
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