Results 201 to 210 of about 375,454 (242)
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
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Damage-associated molecular patterns in tumor radiotherapy
International Immunopharmacology, 2020Radiotherapy is one of the most common modalities for the treatment of cancer. One of the most promising effects of radiotherapy is immunologic cell death and the release of danger alarms, which are known as damage-associated molecular patterns (DAMPs).
Shahram Taeb +2 more
exaly +3 more sources
Role of Damage-Associated Molecular Patterns (DAMPS) in the Postoperative Period after Colorectal Surgery [PDF]
International Journal of Molecular Sciences, 2023 Santiago Cuevas +2 more
exaly +2 more sources
Damage-associated molecular patterns in vitiligo: igniter fuse from oxidative stress to melanocyte loss [PDF]
Redox Report, 2022 Yuanmin He
exaly +2 more sources
Plant immunity by damage-associated molecular patterns (DAMPs)
Essays in Biochemistry, 2022AbstractRecognition by plant receptors of microbe-associated molecular patterns (MAMPs) and pathogenicity effectors activates immunity. However, before evolving the capacity of perceiving and responding to MAMPs and pathogenicity factors, plants, like animals, must have faced the necessity to protect and repair the mechanical wounds used by pathogens ...
Giulia De Lorenzo, Felice Cervone
openaire +2 more sources
Metabolite‐derived damage‐associated molecular patterns in immunological diseases
The FEBS Journal, 2023Damage‐associated molecular patterns (DAMPs) are typically derived from the endogenous elements of necrosis cells and can trigger inflammatory responses by activating DAMPs‐sensing receptors on immune cells. Failure to clear DAMPs may lead to persistent inflammation, thereby contributing to the pathogenesis of immunological diseases.
Na Kang +11 more
openaire +2 more sources
Damage‐associated molecular patterns and immune activation in bipolar disorder
Acta Psychiatrica Scandinavica, 2015ObjectiveImmune activation in bipolar disorder (BD) has been frequently reported. Damage‐associated molecular patterns (DAMPs) are key players in the immune activation reaction. The aim of this study was to assess DAMP levels in drug‐free patients with BD during acute episodes.MethodSerum levels of a predetermined set of DAMPs were assessed in drug ...
Adriane Rosa +2 more
exaly +3 more sources
NEUTROPHIL HETEROGENEITY IN SEPSIS: THE ROLE OF DAMAGE-ASSOCIATED MOLECULAR PATTERNS
Shock, 2022ABSTRACT Sepsis is a severe inflammatory disease syndrome caused by the dysregulated host response to infection. Neutrophils act as the first line of defense against pathogens by releasing effector molecules such as reactive oxygen species, myeloperoxidase, and neutrophil extracellular traps.
Atsushi, Murao +2 more
openaire +2 more sources