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Partial role of TLR4 as a receptor responding to damage-associated molecular pattern
Immunology Letters, 2009Part of pathogen-associated molecular pattern (PAMP) and damage-associated molecular pattern (DAMP) activate antigen-presenting cells through Toll-like receptors (TLRs) to initiate immune responses. However, controversy remains if TLR4 mediates DAMP signaling due to the confounding effects of potential LPS contamination.
Kyung-Mi, Lee, Seung-Yong, Seong
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[DAMPs (damage-associated molecular patterns) and inflammation].
Nihon rinsho. Japanese journal of clinical medicine, 2016Post-ischemic inflammation is re-appraised as an important player in the progression of ischemic stroke. Activation of inflammatory cells via Toll-like receptor 2 (TLR2) and TLR4 is caused by several damage-associated molecular patterns (DAMPs), including high mobility group box-1 (HMGB-1) and heat shock proteins.
Hiroaki, Ooboshi, Takashi, Shichita
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DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis
2016This chapter explores the role of some of the key DAMPs in modulating the coagulation and fibrinolytic cascades, how they activate platelets, and modulate platelet functions. Potential mechanisms differentiating disseminated intravascular coagulation from thrombosis are discussed with an emphasis on the generation of procoagulant membrane remnants that
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Co-incidence of Damage and Microbial Patterns Controls Localized Immune Responses in Roots
Cell, 2020Thomas Lahaye +2 more
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Redox-derived damage-associated molecular patterns: Ligand function of lipid peroxidation adducts
Redox Biology, 2013Koji Uchida
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