Results 51 to 60 of about 407,636 (275)

Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders

open access: yesCells, 2022
Neuroinflammation is a common hallmark in different neurodegenerative conditions that share neuronal dysfunction and a progressive loss of a selectively vulnerable brain cell population.
Cláudia M. Deus   +4 more
doaj   +1 more source

Case Report: Kawasaki disease associated with acute generalized exanthematous pustulosis secondary to carbocysteine

open access: yesFrontiers in Pediatrics
Acute generalized exanthematous pustulosis (AGEP) is an uncommon eruption characterized by sterile pustules on an erythematous background, which is usually associated with drugs. AGEP is described as a self-limiting disease with favorable prognosis.
Takashi Furuta   +5 more
doaj   +1 more source

The Novel Role of Metabolism-Associated Molecular Patterns in Sepsis.

open access: yes, 2022
Sepsis, a life-threatening organ dysfunction, is not caused by direct damage of pathogens and their toxins but by the host's severe immune and metabolic dysfunction caused by the damage when the host confronts infection.
Wang, Shun-Shun   +6 more
core   +1 more source

Enhancing acute inflammatory and sepsis treatment: superiority of membrane receptor blockade

open access: yesFrontiers in Immunology
Conditions such as acute pancreatitis, ulcerative colitis, delayed graft function and infections caused by a variety of microorganisms, including gram-positive and gram-negative organisms, increase the risk of sepsis and therefore mortality.
Seok-Jun Mun   +10 more
doaj   +1 more source

Damage-associated Molecular Patterns in Clinical and Animal Models of Uveitis. [PDF]

open access: yesOcul Immunol Inflamm, 2022
Non-infectious autoimmune uveitis (NIU) in man is a heterogeneous group of diseases characterized by inflammation of the uveal tract and adjacent ocular structures.1 The disease course can be acute...
Kaplan HJ, Sun D, Shao H.
europepmc   +3 more sources

Helicobacter Pylori Infection and Lung Cancer: 
New Insights and Future Challenges

open access: yesChinese Journal of Lung Cancer, 2018
Helicobacter pylori (H. pylori) is the causative agent of chronic gastritis and peptic ulcer diseases and is an important risk factor for the development functional dyspepsia, peptic ulceration, gastric adenocarcinoma and mucosa-associated lymphoid ...
Ileana GONZÁLEZ   +2 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Plant–Plant Communication: Is There a Role for Volatile Damage-Associated Molecular Patterns? [PDF]

open access: yesFrontiers in Plant Science, 2020
Damage-associated molecular patterns (DAMPs) are an ancient form of tissue-derived danger or alarm signals that initiate cellular signaling cascades, which often initiate defined defense responses. A DAMP can be any molecule that is usually not exposed to cells such as cell wall components, peptides, nucleic acid fragments, eATP and other compounds ...
Meents, A., Mithöfer, A.
openaire   +4 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

N-Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells—An In Vitro Model for Early Inflammatory Profiling of Schwann Cells

open access: yesCells, 2020
Following nerve injury, disintegrated axonal mitochondria distal to the injury site release mitochondrial formylated peptides and DNA that can induce activation and inflammatory profiling of Schwann cells via formyl peptide receptor 2 (Fpr2) and toll ...
Andrea Korimová, Petr Dubový
doaj   +1 more source

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