Results 61 to 70 of about 407,636 (275)

The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma [PDF]

, 2007
Aims: To clarify MUC1 patterns in invasive ductal breast carcinoma and to relate them to clinicopathological parameters, coexpression of other biological markers and prognosis.
de Bock, G. H., de Bock, G. H.; id_orcid, de Roos, M.A.J., van der Vegt, B.; id_orcid, Hilkens, J., Patriarca, C., Peterse, J. L., van der Vegt, B., Peterse, J.L., de Bock, G.H., Wesseling, J.   +10 more
core   +1 more source

The role of damage associated molecular patterns during posttraumatic coagulopathy

, 2023
Polytrauma and related hemostatic disorders are still and will likely continue to be a serious burden for health care around the world. Coagulation in patients with severe trauma can initially be impaired by acidosis, hypothermia and iatrogenic ...
Müller, Frederik
core   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Construction of a Novel Damage-Associated Molecular-Pattern-Related Signature to Assess Lung Adenocarcinoma’s Prognosis and Immune Landscape

Biomolecules
Immunogenic death (ICD) stimulates adaptive immunity and affects immunotherapeutic efficacy, an important part of which is damage-associated molecular patterns (DAMPs).
Xinyue Liu, Shuxi Yao, Yanqi Feng, Piao Li, Yiming Li, Shu Xia   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Regulation of neuroimmune processes by damage- and resolution-associated molecular patterns

Neural Regeneration Research, 2021
Sterile inflammatory processes are essential for the maintenance of central nervous system homeostasis, but they also contribute to various neurological disorders, including neurotrauma, stroke, and demyelinating or neurodegenerative diseases.
Andis Klegeris
doaj   +1 more source

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

, 2011
Cell death and injury often lead to release or exposure of intracellular molecules called damage-associated molecular patterns (DAMPs) or cell death-associated molecules.
Lambrecht, Bart, Claus Bachert, Bachert, Claus, Olga Krysko, Patrizia Agostinis, Krysko, Dmitri V., Krysko, Olga, Dmitri V. Krysko, Bart N. Lambrecht, Abhishek D. Garg, Vandenabeele, Peter, Garg, Abhishek, Agostinis, Patrizia, Garg, Abhishek D, Lambrecht, Bart N., Krysko, Dmitri, Peter Vandenabeele   +16 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Engineering plant resistance by constructing chimeric receptors that recognize damage-associated molecular patterns (DAMPs)

, 2011
An efficient sensing of danger and a rapid activation of the immune system are crucial for the survival of plants. Conserved pathogen/microbe-associated molecular patterns (PAMPs/MAMPs) and endogenous molecular patterns, which are present only when the ...
DE LORENZO, Giulia, Giulia De Lorenzo, SICILIA, Francesca, Daniel Valentin Savatin, Felice Cervone, SAVATIN, DANIEL VALENTIN, Francesca Sicilia, Brutus, Alexandre, CERVONE, Felice, Alexandre Brutus   +9 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source