Results 161 to 170 of about 59,000 (187)
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DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis
2016This chapter explores the role of some of the key DAMPs in modulating the coagulation and fibrinolytic cascades, how they activate platelets, and modulate platelet functions. Potential mechanisms differentiating disseminated intravascular coagulation from thrombosis are discussed with an emphasis on the generation of procoagulant membrane remnants that
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Activation of murine γδ T-cells by mitochondrial damage-associated molecular patterns (DAMPS) (45.4)
The Journal of Immunology, 2012Abstract Gamma delta T-cells have been shown to be important in the early immunoinflammatory response to injury, which can be independent of infection. This sterile inflammatory response is in part associated with DAMPs. Mitochondrial DAMPs (MTDs) have been shown to be important in trauma-induced neutrophil activation, but it is unknown ...
Martin Schwacha +2 more
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Hypertension, 2012
Aims: Vascular injury including edema and hemorrhage after ischemic stroke is increased in diabetes. High-mobility group box 1 (HMGB1) is a DAMP passively released by necrotic cells that initiates pro-inflammatory signaling through binding to the TLR4 receptor.
Mohammed A Abdelsaid +6 more
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Aims: Vascular injury including edema and hemorrhage after ischemic stroke is increased in diabetes. High-mobility group box 1 (HMGB1) is a DAMP passively released by necrotic cells that initiates pro-inflammatory signaling through binding to the TLR4 receptor.
Mohammed A Abdelsaid +6 more
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2009
Introduction: Systemic juvenile idiopathic arthritis (sJIA) is chronic childhood arthritis of unknown cause. Novel studies seem to point to deregulation of the innate immune system as the primary pathophysiological mechanism, thus making sJIA an auto-inflammatory disorder. Aim: To explore the involvement of alarmins in the pathogenesis of sJIA Patients
Malčić, Ivan +4 more
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Introduction: Systemic juvenile idiopathic arthritis (sJIA) is chronic childhood arthritis of unknown cause. Novel studies seem to point to deregulation of the innate immune system as the primary pathophysiological mechanism, thus making sJIA an auto-inflammatory disorder. Aim: To explore the involvement of alarmins in the pathogenesis of sJIA Patients
Malčić, Ivan +4 more
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DNA damage and repair in age-related inflammation
Nature Reviews Immunology, 2022Yang Zhao +2 more
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Female erectile tissues and sexual dysfunction after pelvic radiotherapy: A scoping review
Ca-A Cancer Journal for Clinicians, 2022Deborah C Marshall, Mas +2 more
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Nuclear DNA damage signalling to mitochondria in ageing
Nature Reviews Molecular Cell Biology, 2016Evandro Fei Fang +2 more
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The DNA damage response to transcription stress
Nature Reviews Molecular Cell Biology, 2019Hannes Lans +2 more
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DNA damage and the balance between survival and death in cancer biology
Nature Reviews Cancer, 2015Wynand P Roos +2 more
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Therapeutic opportunities within the DNA damage response
Nature Reviews Cancer, 2015Laurence H Pearl +2 more
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