Characteristics of Scar Formation After Intracerebral Hemorrhage in Aged Rats: Effects of Deferoxamine [PDF]
CellsIntracerebral hemorrhage (ICH), a severe stroke subtype common in the elderly, often results in high morbidity and mortality, with limited treatment options for long-term recovery.
Xiongjie Fu +4 more
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Platelet Membrane-Based Nanoparticles for Targeted Delivery of Deferoxamine to Alleviate Brain Injury Induced by Ischemic Stroke [PDF]
International Journal of NanomedicinePeina Wang,1,2,* Xin Lv,1,* Siyu Tian,1 Wen Yang,2 Mudi Feng,1 Shiyang Chang,2 Linhao You,1 Yan-Zhong Chang1 1Laboratory of Molecular Iron Metabolism, Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei ...
Wang P +7 more
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Restoring the Angiogenic Capacity of the Human Diabetic Adipose-derived mesenchymal stem cells Primed with Deferoxamine as a Hypoxia Mimetic Agent: Role of HIF-1α [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Insufficient angiogenesis is associated with serious diabetic complications. Recently, adipose-derived mesenchymal stem cells (ADScs) are known to be a promising tool causing therapeutic neovascularization.
Raziye Tajali +4 more
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Deferoxamine B: A Natural, Excellent and Versatile Metal Chelator
Molecules, 2021 Deferoxamine B is an outstanding molecule which has been widely studied in the past decade for its ability to bind iron and many other metal ions.
Denise Bellotti, Maurizio Remelli
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Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. [PDF]
PLoS Pathogens, 2015 Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae.
Mingfu Liu +8 more
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Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis
Neural Regeneration Research, 2019 Ferroptosis is an iron-dependent novel cell death pathway. Deferoxamine, a ferroptosis inhibitor, has been reported to promote spinal cord injury repair.
Xue Yao +14 more
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BMC Ophthalmology, 2021 Background Deferoxamine retinopathy is the informally designated term used to describe a characteristic pattern of outer retinal degeneration in iron-overloaded chronic anemia patients who are treated with deferoxamine. We hypothesize that insufficiently
Mohamed Belmouhand +5 more
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Chelating the valley of death: Deferoxamine’s path from bench to wound clinic
Frontiers in Medicine, 2023 There is undisputable benefit in translating basic science research concretely into clinical practice, and yet, the vast majority of therapies and treatments fail to achieve approval.
Jennifer B. Parker +10 more
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Journal of Pharmaceutical Health Care and Sciences, 2023 Background Erythrocyte transfusion is an indispensable component of supportive care after hematopoietic stem cell transplantation (HSCT). However, HSCT recipients are susceptible to the development of acute kidney injury (AKI) with multifactorial causes.
Hirokazu Nakayama +4 more
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Wnt5a is a key target for the pro-osteogenic effects of iron chelation on osteoblast progenitors
Haematologica, 2016 Iron overload due to hemochromatosis or chronic blood transfusions has been associated with the development of osteoporosis. However, the impact of changes in iron homeostasis on osteoblast functions and the underlying mechanisms are poorly defined ...
Ulrike Baschant +6 more
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