Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. [PDF]
PLoS Pathogens, 2015 Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae.
Mingfu Liu +8 more
doaj +4 more sources
Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation [PDF]
ChemistryOpenPolymeric systems are used in clinical settings to bind small molecules and ions. They show advantages in pharmacokinetics and reduced side effects compared to low‐molecular‐weight agents.
Roberta Panebianco +2 more
doaj +2 more sources
Deferoxamine-Loaded Chitosan-Based Hydrogel on Bone Implants Showing Enhanced Bond Strength and Pro-Angiogenic Effects [PDF]
Journal of Functional BiomaterialsAngiogenesis is vital for bone fracture healing and plays a significant role in the fate of orthopedic implants. The growth and maintenance of new blood vessels at the fracture site of patients is essential, which promotes the clinical outcome of plasma ...
Huan Liu +5 more
doaj +2 more sources
Effects of combined deferiprone with deferoxamine on right ventricular function in thalassaemia major [PDF]
Journal of Cardiovascular Magnetic Resonance, 2012 Background Combination therapy with deferoxamine and oral deferiprone is superior to deferoxamine alone in removing cardiac iron and improving left ventricular ejection fraction (LVEF).
Alpendurada Francisco +9 more
doaj +4 more sources
Comparative efficacy of deferiprone, deferoxamine and combination of deferiprone and deferoxamine on serum ferritin value in Beta-Thalassemia patients [PDF]
, 2015 Background: Iron overload is a predictable and life-threatening complication in patients with thalassemia. Effective and convenient iron chelation remains one of the main targets of clinical management of thalassemia major.
Amlashi, H.M. +3 more
core +2 more sources
Disrupting cell death: ferroptosis and pyroptosis inhibition in hepatic ischemia-reperfusion injury via modulation of GPX4 and cGAS pathways by deferoxamine and octreotide. [PDF]
Front PharmacolTawfiq RA +3 more
europepmc +3 more sources
Deferoxamine Inhibits Canine Parvovirus by Suppressing Ferroptosis and Viral Replication [PDF]
Veterinary SciencesCPV is a highly pathogenic virus that enters host cells via the TFR, but its pathogenic mechanisms are not fully understood. In this study, we demonstrated that CPV infection induces ferroptosis in CRFK cells, characterized by elevated lipid peroxidation,
Kai Yu +16 more
doaj +2 more sources
Restoring the Angiogenic Capacity of the Human Diabetic Adipose-derived mesenchymal stem cells Primed with Deferoxamine as a Hypoxia Mimetic Agent: Role of HIF-1α [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Insufficient angiogenesis is associated with serious diabetic complications. Recently, adipose-derived mesenchymal stem cells (ADScs) are known to be a promising tool causing therapeutic neovascularization.
Raziye Tajali +4 more
doaj +1 more source
Early neurological improvement with deferoxamine after intracerebral hemorrhage: A post hoc analysis of the i-DEF trial. [PDF]
Int J StrokePolymeris AA +11 more
europepmc +2 more sources
An overview of complications associated with deferoxamine therapy in thalassemia [PDF]
Journal of Nephropharmacology, 2021 Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei +5 more
doaj +1 more source