Results 91 to 100 of about 14,894 (236)
Functional Cargo in Membrane Vesicles From a Citrus Pathogen
ABSTRACT The causative agent of citrus canker disease, Xanthomonas citri pv. citri, was found to produce copious amounts of outer membrane vesicles (OMVs), frequently forming long membranous tubes under different culture conditions. Lipidomic analysis revealed significant differences in lipid composition between purified vesicles in relation to whole ...
Gabriel G. Araujo+14 more
wiley +1 more source
Nuclear Import Defects Drive Cell Cycle Dysregulation in Neurodegeneration
Overview of Dysregulated Cell Cycle Mechanisms in Neuronal Cells. A nuclear import block drives cell cycle re‐entry from G0, culminating in cell cycle arrest at G1/S. This cell cycle arrest is associated with activation of CKIs from the INK locus (p15, p16, p18, p19) and Cip/Kip (p21, p27) which act on specific CDK/Cyclin complexes.
Jonathan Plessis‐Belair+3 more
wiley +1 more source
The Role of Iron in Hemorrhagic Stroke
Sravanthi Koduri+4 more
doaj +1 more source
Deferoxamine treatment during pregnancy: Is it harmful? [PDF]
Sylvia T. Singer, Elliott Vichinsky
openalex +1 more source
Our study explores the potential of dauricine, a bioactive compound from Menispermum dauricum, to overcome osimertinib resistance in lung cancer. We demonstrate that dauricine, when combined with osimertinib, induces ferroptosis in resistant lung cancer cells by stabilizing SAT1, a key enzyme in oxidative stress regulation.
Biying Men+16 more
wiley +1 more source
Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support [PDF]
S Farinelli, LA Greene
openalex +1 more source
ACSM5 induced ferroptosis in HCC by up‐regulating cytochrome P450 oxidoreductase (POR). The metabolic transformation of linoleic acid to arachidonic acid was also promoted by ACSM5; thereby, the sensitivity to ferroptosis was elevated. ABSTRACT The medium‐chain fatty acyl‐CoA synthetase‐5 (ACSM5) plays a crucial role in the development of some cancers.
Zhengqiang Wu+8 more
wiley +1 more source
ABSTRACT Chronic and non‐healing wounds are a global health issue with limited effective treatments. Wound care costs continue to rise, highlighting the need for new therapies. Medicinal plants, particularly African species, show promise for enhancing wound healing.
Philisiwe F. Molefe+6 more
wiley +1 more source
Salvianolic Acid B Attenuates Ferroptosis in Acute Kidney Injury by Targeting PRDX5
Mechanistic diagram of SAB‐mediated alleviation of AKI through the regulation of PRDX5‐mediated ferroptosis in renal tubular epithelial cells. SAB alleviates cisplatin‐ and FA‐induced AKI by inhibiting ferroptosis via PRDX5‐mediated upregulation of SLC7A11, GPX4, and FSP1.
Yan Tao+5 more
wiley +1 more source
The Effect of Deferoxamine (DFO) on Postasphyxial Cerebral Reperfusion Injury. 220 [PDF]
Majidah Shadid+6 more
openalex +1 more source