Results 161 to 170 of about 11,663 (212)

Delphinidin and Its Glycosides’ War on Cancer: Preclinical Perspectives [PDF]

International Journal of Molecular Sciences, 2021
Until now, several studies have looked at the issue of anthocyanin and cancer, namely the preventive and inhibitory effects of anthocyanins, as well as the underlying molecular processes. However, no targeted review is available regarding the anticarcinogenic effects of delphinidin and its glycosides on various cancers and their plausible molecular ...
Hae-Jeung Lee, Hyo-Kyoung Choi, Anshul Sharma   +2 more
exaly   +4 more sources

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Effect of Delphinidin on Metabolomic Profile in Breast Carcinogenesis

Anti-Cancer Agents in Medicinal Chemistry, 2022
Background: Breast cancer is a malignant tumor which threat to women’s physical and mental health. Delphinidin, one of the main anthocyanidins, has potent anti-cancer properties. In previous study, we found that delphinidin has the preventive role in MNU-induced breast carcinogenesis of rats, but the molecular mechanism by which delphinidin combats ...
Bin, Han, Fanqi, Meng, Yun, Niu, Hao, Liu, Ju, Li, Xiaoli, Peng   +5 more
openaire   +2 more sources

Antioxidant activity of delphinidin and pelargonidin: Theory and practice

Journal of Food Biochemistry, 2022
The quantum chemical density functional theory and in vitro chemical-based antioxidant assays were used to research the reaction mechanism of delphinidin/pelargonidin with free radicals including superoxide anion radicals (O2 - ∙) and hydroperoxide radicals (OOH∙). The geometric configuration, bond dissociation energy, PCM (polarizable continuum model)
Hongan Li, Chengyue Zhang, Zeyuan Deng, Bing Zhang, Hongyan Li   +4 more
openaire   +2 more sources

Molecular Structure and Antioxidant Properties of Delphinidin

The Journal of Physical Chemistry A, 2008
Density functional theory calculations were performed to evaluate the antioxidant activity of delphinidin, taking into account its acid/base equilibrium. The conformational behavior of both the isolated and the aqueous solvation species (simulated with the polarizable continuum model) were analyzed at the B3LYP/6-31++G(d,p) level, considering the ...
Laura, Estévez, Ricardo A, Mosquera
openaire   +2 more sources

Delphinidin 3-arabinoside in the Epacridaceae

Phytochemistry, 1971
Abstract A new anthocyanin, delphinidin 3-arabinoside, has been isolated and identified from seven species of the family Epacridaceae.
S.J. Jarman, R.K. Crowden
openaire   +1 more source

Delphinidin Increases the Sensitivity of Ovarian Cancer Cell Lines to 3-bromopyruvate [PDF]

International Journal of Molecular Sciences, 2021
3-Bromopyruvic acid (3-BP) is a promising anticancer compound. Two ovary cancer (OC) cell lines, PEO1 and SKOV3, showed relatively high sensitivity to 3-BP (half maximal inhibitory concentration (IC50) of 18.7 and 40.5 µM, respectively). However, the further sensitization of OC cells to 3-BP would be desirable.
Izabela Sadowska-Bartosz, Grzegorz Bartosz, Natalia Pieńkowska   +2 more
exaly   +3 more sources

Acylated delphinidin glycosides in the blue-violet flowers of Consolida armeniaca

Phytochemistry, 1996
Four new acylated delphinidin 3,7-glycosides were isolated from the blue-violet flowers of Consolida armeniaca as major anthocyanin pigments. The first pigment was based on delphinidin 3,7-diglucoside and was identified as delphinidin 3-O-[6-O-(malonyl)-beta-D-glucopyranoside]-7-O- [6-O-(4-O-(6-O-(p-hydroxybenzoyl)-beta-D-glucopyranosyl)-p ...
Kenjiro Toki, Seçkin Ozden
exaly   +3 more sources

The Multifunctional Benefits of Naturally Occurring Delphinidin and Its Glycosides

Journal of Agricultural and Food Chemistry, 2019
Delphinidin (Del) and its glycosides are water-soluble pigments, belonging to a subgroup of flavonoids. They are health-promoting candidates for pharmaceutical and nutraceutical uses, as indicated by exhibiting antioxidation, anti-inflammation, antimicroorganism, antidiabetes, antiobesity, cardiovascular protection, neuroprotection, and anticancer ...
Zhixi Chen, Rui Zhang, Weimei Shi, Linfu Li, Hai Liu, Zhiping Liu, Longhuo Wu   +6 more
openaire   +2 more sources

Delphinidin Induces Autolysosome as well as Autophagosome Formation and Delphinidin‐Induced Autophagy Exerts a Cell Protective Role

Journal of Biochemical and Molecular Toxicology, 2012
ABSTRACTAnthocyanidins, which are polyphenols that are believed to be effective for preventing cancer, are composed of a basic structure of the plant pigment anthocyanin. In this study, we investigated the biological activity of anthocyanidins, including delphinidin, against HeLa cells.
Satoshi, Tsuyuki, Sayuri, Fukui, Akari, Watanabe, Satoshi, Akune, Mizuki, Tanabe, Kenichi, Yoshida   +5 more
exaly   +3 more sources

Blockade of the Renin-Angiotensin System with Delphinidin, Cyanin, and Quercetin

Planta Medica, 2012
Overactivation of the renin-angiotensin system is one of the most important risk factors for the development of hypertension. The use of the crude extracts and/or active compounds, such as anthocyanins and quercetin, of herbal plants that have antihypertensive effects is beneficial for decreasing of blood pressure level.
Warisara, Parichatikanond, Darawan, Pinthong, Supachoke, Mangmool   +2 more
openaire   +2 more sources