Results 151 to 160 of about 9,026 (183)

Delphinidin Prevents Muscle Atrophy and Upregulates miR-23a Expression

Journal of Agricultural and Food Chemistry, 2016
Delphinidin, one of the major anthocyanidins, shows protective effects against a variety of pathologies, including cancer, inflammation, and muscle atrophy. The purpose of this study was to determine the preventive mechanism of delphinidin on disuse muscle atrophy.
Motoki Murata, Haruna Nonaka, Satomi Komatsu, Megumi Goto, Mai Morozumi, Shuhei Yamada, I-Chian Lin, Shuya Yamashita, Hirofumi Tachibana   +8 more
openaire   +2 more sources

Delphinidin Modulates the DNA-Damaging Properties of Topoisomerase II Poisons

Chemical Research in Toxicology, 2009
The anthocyanidin delphinidin (DEL) has recently been shown to inhibit human topoisomerase I and II, without stabilizing the covalent DNA/topoisomerase intermediate [Habermeyer, M., Fritz, J., Barthelmes, H. U., Christensen, M. O., Larsen, M. K., Boege, F., and Marko, D.
Melanie, Esselen, Jessica, Fritz, Melanie, Hutter, Doris, Marko   +3 more
openaire   +2 more sources

Effects of the natural flavonoid delphinidin on diabetic microangiopathy.

Arzneimittel-Forschung, 1995
The purpose of the present study was to investigate the effects of the flavonoid delphinidin chloride (CAS 528-53-0, IdB 1056) on diabetic microangiopathy. Hamsters were injected with alloxan and cheek pouch microcirculation was observed by a fluorescent microscopy technique 90 days from alloxan.
BERTUGLIA S., MALANDRINO S., COLANTUONI, ANTONIO   +2 more
openaire   +3 more sources

Design, Synthesis, Pharmacological Evaluation and Vascular Effects of Delphinidin Analogues

Current Pharmaceutical Design, 2019
Background: Among polyphenolic compounds suggested to prevent cardiovascular diseases (CVDs) and to explain the “French paradox”, the anthocyanidin delphinidin (Dp) has been reported to support at least partly the vascular beneficial effects of dietary polyphenolic compounds including those from fruits and related products as red wine.
Samuel, Legeay, Kien, Trân, Yannick, Abatuci, Hélène, Justiniano, Claire, Lugnier, Olivier, Duval, Jean-Jacques, Helesbeux, Sébastien, Faure   +7 more
openaire   +2 more sources

Comparison of the Inhibitory Effects of Delphinidin and Its Glycosides on Cell Transformation

Planta Medica, 2014
Although anthocyanins are major forms distributed in many plant foods and promising as chemopreventive source, many molecular data are obtained from anthocyanidins, showing their low bioavailability. This study aims to clarify the inhibitory effects of delphinidin glycosides on cell transformation comparing them to those of delphinidin.
Takayuki, Sogo, Takuma, Kumamoto, Hisako, Ishida, Ayami, Hisanaga, Kozue, Sakao, Norihiko, Terahara, Koji, Wada, De-Xing, Hou   +7 more
openaire   +2 more sources

Delphinidin: A Multifaceted Anthocyanidin With Therapeutic Potential in Chronic Diseases

Journal of Biochemical and Molecular Toxicology
ABSTRACT Delphinidin, a bioactive anthocyanidin found in pigmented fruits and vegetables, exhibits remarkable therapeutic potential due to its antioxidant, anti‐inflammatory, and anti‐cancer properties. This review synthesizes current knowledge on delphinidin's structure, dietary sources, stability challenges, and mechanisms of action.
Bidemi Emmanuel, Ekundayo, Abraham Olabode, Ademola, Motunrayo Comfort, Ekundayo, Opeyemi O, Deji-Oloruntoba, Etuvie Favour, Akomolafe, Busayo Kayode, Akomolafe, Basiru Olaitan, Ajiboye, Babatunji Emmanuel, Oyinloye   +7 more
openaire   +2 more sources

The effect of delphinidin on the mechanical properties of keratinocytes exposed to UVB radiation

Journal of Photochemistry and Photobiology B: Biology, 2016
The usage of active compounds of dietary phytochemicals in prevention of UV-induced skin diseases is increasingly gaining attention in the development of skin care products. The purpose of this study was to measure the influence of delphinidin (as a botanical agent) on the cell mechanical properties evaluated by the atomic force microscopy (AFM ...
Anna, Sobiepanek, Małgorzata, Milner-Krawczyk, Konstancja, Bobecka-Wesołowska, Tomasz, Kobiela   +3 more
openaire   +2 more sources

New delphinidin glycosides isolated fromVinca major flowers

The Botanical Magazine Tokyo, 1978
Four kinds of delphinidin glycoside were found in the bluish-purple flowers ofVinca major. Among them, two glycosides were isolated in a crystalline state by application of Sephadex and Avicel columns. The names of vincanin A and vincanin B were tentatively assigned to those new glycosides.
Nariyuki Ishikura, Katsuyoshi Minekishi
openaire   +1 more source

Impact of Delphinidin on the Maintenance of DNA Integrity in Human Colon Carcinoma Cells

Journal of Agricultural and Food Chemistry, 2008
Delphinidin has been found to possess DNA strand-breaking properties in cell culture. In the present study, we demonstrated that the extent of DNA damage by delphinidin is not affected by the expression of tyrosyl-DNA-phosphodiesterase 1, indicating that the induction of DNA strand breaks is not predominantly topoisomerase-mediated.
Jessica, Fritz, Matthias, Roth, Peter, Holbach, Melanie, Esselen, Doris, Marko   +4 more
openaire   +2 more sources

An acylated delphinidin glycoside in the blue flowers of Evolvulus pilosus

Phytochemistry, 1994
Abstract A new acylated anthocyanin was isolated from the blue flowers of Evolvulus pilosus cv ‘Blue Daze’ as a major anthocyanin. The structure of this pigment was determined to be delphinidin 3- O -(6- O -( trans -4- O -(6- O -( trans -3- O -(β-d-glucopyranosyl)-caffeyl)-β-d-glucopyranosyl)-caffeyl)-β-d-glucopyranoside)-5- O -((6- O -malonyl)-β-d-
Kenjiro Toki, Norio Saito, Kazuko Kawano, Tin Sen Lu, Atsushi Shigihara, Toshio Honda   +5 more
openaire   +1 more source