Results 21 to 30 of about 2,772 (159)
Molecules, 2022 In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu +11 more
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Toxins, 2018 The emetic syndrome of Bacillus cereus is a food intoxication caused by cereulide (CER) and manifested by emesis, nausea and in most severe cases with liver failure. While acute effects have been studied in the aftermath of food intoxication, an exposure
Marlies Decleer +7 more
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A New Depsipeptide Antibiotic, Variapeptin [PDF]
Agricultural and Biological Chemistry, 1990 A culture similar to Streptomyces variabilis was found to produce a novel cyclic hexadepsipeptide antibiotic named variapeptin. Variapeptin is structurally related to azinothricin, A83586C, and citropeptin. The antibiotic was active against Gram-positive bacteria and showed cytotoxic activity against mammalian cells.
M, Nakagawa +3 more
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Chemical Classification of Cyclic Depsipeptides
Current Protein & Peptide Science, 2017 Cyclic depsipeptides (CDPs) are a family of cyclic peptide-related compounds, of which the ring is mainly composed of amino- and hydroxy acid residues joined by amide and ester bonds (at least one), leading to a wide diversity of fascinating chemical structures. They differ in both their ring structure and their side chains, especially by the nature of
Taevernier, Lien +3 more
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Frontiers in Catalysis, 2023 In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides.
Y. T. Candace Ho +28 more
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Molecules, 2017 The study assessed a radiolabeled depsipeptide conjugate (68Ga-DOTA-TBIA101) for its potential as an imaging agent targeting infection or infection-associated inflammation. 68Ga-labeled DOTA-TBIA101 imaging was performed in (NZR1) healthy rabbits; (NZR2)
Thomas Ebenhan +5 more
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“Head-to-Side-Chain” Cyclodepsipeptides of Marine Origin
Marine Drugs, 2013 Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as “head-to-side-chain” cyclodepsipeptides, have been isolated and characterized.
Marta Pelay-Gimeno +2 more
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Synthetic strategies of phosphonodepsipeptides
Beilstein Journal of Organic Chemistry, 2021 Phosphonodepsipeptides are phosphorus analogues of depsipeptides and phosphonate-linked analogues of naturally occurring peptides. They are more stable than phosphonopeptides and have been widely applied as enzyme inhibitors, haptens for the production ...
Jiaxi Xu
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CHIMIA, 1983 Synthesis of phosphorous analogues of tri- and tetra-depsipeptides 4 involving the Passerini reaction of diethylisocyanmethylphosphonate 3 with carbonyl compounds 2 and N-protected glycine 1 is reported.
Janusz Rachoń
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Marine Drugs, 2023 This study aimed to elucidate the structural congeners of natural izenamides A, B, and C (1–3) responsible for cathepsin D (CTSD) inhibition. Structurally modified izenamides were synthesized and biologically evaluated, and their biologically important ...
Hyun Su Kim +6 more
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