Results 51 to 60 of about 2,772 (159)
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian +3 more
wiley +1 more source
Antibiotics produced by symbiotic microorganisms were previously shown to be of crucial importance for ecological communities, including ants. Previous works on ant–actinobacteria symbiosis are mainly focused on farming ants, which use antifungal ...
Anna A. Baranova +7 more
doaj +1 more source
This review provides a fresh overview of non-canonical amino acids and their applications in the design of peptidomimetics. Non-canonical amino acids appear widely distributed in nature and are known to enhance the stability of specific secondary ...
Tarsila G. Castro +4 more
doaj +1 more source
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli +8 more
wiley +1 more source
The V‐Shaped Hamilton Receptors: A Paradigmatic Multipurpose Scaffold
This manuscript explores the historical context and significance of molecular recognition in relation to Hamilton‐type receptors. It concludes with a discussion on future prospects for the development of novel functionalized Hamilton‐type receptors. It is hoped that this collection will offer new insights and directions for the supramolecular chemistry
Shafieq Ahmad Wagay, Rashid Ali
wiley +1 more source
Activating hidden signals by mimicking cryptic sites in a synthetic extracellular matrix
Cryptic sites are short signaling peptides buried within the native extracellular matrix (ECM). Enzymatic cleavage of an ECM protein reveals these hidden peptide sequences, which interact with surface receptors to control cell behavior.
Yumeng Zhu +5 more
doaj +1 more source
Bioactive peptides are chemical compounds created through the covalent bonding of amino acids, known as amide or peptide bonds. Due to their unusual chemistry and various biological effects, marine bioactive peptides have garnered considerable research ...
Norma Flores-Holguín +2 more
doaj +1 more source
A contribution to the nomenclature of depsipeptides [PDF]
AbstractDepsipeptides, also called peptolides, are a class of peptidic compounds in which an amide bond has been replaced with an ester bond. The literature does not clearly display rules for the nomenclature of such compounds. Here a method is proposed to transcribe drawn depsipeptide structures in one‐line text.
Sorin V, Filip, Florine, Cavelier
openaire +2 more sources
Robust Synthesis of Prebiotic Precursors in Drying Reactions of Amino Acids and Keto Acids
Drying conditions drive reactions between amino acids and keto acids, generating a wide variety of small, reactive species, highlighting for the first time the potential significance of drying reactions in proto‐metabolism on early Earth. Condensation‐dehydration reactions are critical to both metabolism and polymerization in extant biology, and their ...
Eliav Marland +7 more
wiley +1 more source
Investigation of an extract from the marine cyanobacterium Lyngbya semiplena, collected in Tumon Bay, Guam, led to the identification of three new cyclodepsipeptides, lyngbyastatins 8–10 (1–3).
Hendrik Luesch +3 more
doaj +1 more source

