Results 91 to 100 of about 16,428 (265)
Tumor Glycosylation: A Main Player in the Modulation of Immune Responses
European Journal of Immunology, Volume 55, Issue 3, March 2025.Cancer cells present aberrant glycosylation patterns that contribute to the evasion of antitumor immunity by triggering lectin receptors. Therefore, tumor glycosylation represents an interesting target for novel immunotherapy strategies. This review discusses the different mechanisms by which tumor‐derived glycans induce tolerogenic programs in immune ...
Ernesto Rodriguez
wiley +1 more source
Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan [PDF]
, 2000 It has been proposed that hyaluronan-binding proteoglycans play an important role as guiding cues during neural crest (NC) cell migration, but their precise function has not been elucidated.
Bellina, Isabella +11 more
core
Brazilian Journal of Medical and Biological Research, 2001 The anticlotting and antithrombotic activities of heparin, heparan sulfate, low molecular weight heparins, heparin and heparin-like compounds from various sources used in clinical practice or under development are briefly reviewed.
H.B. Nader +12 more
doaj +1 more source
Mucopolysaccharidosis type I - Clinical and genetic characteristics of Romanian patients
Romanian Journal of Laboratory Medicine, 2020 Background: Mucopolysaccharidosis type I (MPS I) is an autosomal recessive lysosomal storage disorder caused by a deficiency of α-L-iduronidase (IDUA), which leads to the accumulation of partially digested glycosaminoglycans (dermatan sulfate and heparan
Alkhzouz Camelia +6 more
doaj +1 more source
Ultrasensitive quantification of dextran sulfate by a mix-and-read fluorescent probe assay [PDF]
arXiv, 2017 Dextran sulfate is semi-synthetic, polydisperse sulfated polysaccharide with important applications in clinical practice, in the manufacturing of plasma derived protein therapeutics and in biomedical research. The sensitive detection of dextran sulfate is relevant to preclinical and clinical drug development projects, the quality control of ...
arxiv
Retrospective Study of Clinical and Genetic Profiles of Alpha‐Mannosidosis Patients From the UAE
JIMD Reports, Volume 66, Issue 2, March 2025.ABSTRACT Alpha‐mannosidosis (AM; OMIM 248500) is a rare autosomal recessive lysosomal storage disorder caused by mutations in MAN2B1, which codes for the lysosomal alpha‐mannosidase enzyme (LAMAN; EC:3.2.1.24). Clinical characteristics include developmental delay, hearing impairment, and recurrent infections.
Ali K. Saad +6 more
wiley +1 more source
FROM GENE TO STRUCTURE: Formation of Iduronic Acid in Dermatan Sulfate by Two DS-epimerases [PDF]
, 2008 During embryonic development and adult life a wide range of cell behaviors such as differentiation, proliferation and migration are in effect to maintain tissue integrity and function.
Pacheco, Benny
core
Orphanet Journal of Rare Diseases, 2010 Mucopolysaccharidosis VI (MPS VI) is a lysosomal storage disease with progressive multisystem involvement, associated with a deficiency of arylsulfatase B leading to the accumulation of dermatan sulfate. Birth prevalence is between 1 in 43,261 and 1 in 1,
Harmatz Paul +3 more
doaj +1 more source
Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells. [PDF]
, 1983 We have examined the morphology, cytochemistry, and biochemistry of mouse leukocyte subsets by analyzing cloned leukocyte populations specialized to perform different immunologic functions.
Cantor, H +10 more
core
Cardiovascular Diabetology, 2004 Background Arterial proteoglycans are implicated in the pathogenesis of atherosclerosis by their ability to trap plasma lipoproteins in the arterial wall and by their influence on cellular migration, adhesion and proliferation.
Litwak Kenneth N +4 more
doaj +1 more source