Results 21 to 30 of about 16,428 (265)
Shipin gongye ke-ji, 2022 Taking permeate liquid in the process of extracting heparin from porcine intestinal mucosa as raw material, the extraction process of dermatan sulfate was optimized to explore the antioxidant capacity of dermatan sulfate.
Yubao WANG +9 more
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Novel Insight Into Glycosaminoglycan Biosynthesis Based on Gene Expression Profiles
Frontiers in Cell and Developmental Biology, 2021 Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate, except for hyaluronan that is a free polysaccharide, are covalently attached to core proteins to form proteoglycans.
Yi-Fan Huang +2 more
doaj +1 more source
Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components. [PDF]
, 2013 Background Proteases expressed in atherosclerotic plaque lesions generate collagen fragments, release glycosaminoglycans (chondroitin sulfate [CS] and dermatan sulfate [DS]) and expose extracellular matrix (ECM) proteins (e.g.
Bóta, Attila +7 more
core +5 more sources
Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer [PDF]
PeerJ, 2021 Background Dysregulation of glycogene expression in cancer can lead to aberrant glycan expression, which can promote tumorigenesis. Cervical cancer (CC) displays an increased expression of glycogenes involved in sialylation and sialylated glycans.
Patricia Martinez-Morales +8 more
doaj +2 more sources
Structure of Dermatan Sulfate And Its Anticoagulant
Trends in Glycoscience and Glycotechnology, 1996 Masayuki Ishihara
openalex +4 more sources
Studies on the biosynthesis of dermatan sulfate [PDF]
FEBS Letters, 1971 It is generally accepted that the biosynthesis of polysaccharide proteins in mammalian tissues follows a certain schedule [ 1,2] involving four principal steps: (a) formation of the polypeptide backbone, (b) stepwise addition of monosaccharide units from the appropiate nucleotide sugars to form the linkage j e ion to protein, and (c) the alternate ...
A. Malmström, Lars-Åke Fransson
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Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis. [PDF]
PLoS ONE, 2015 The epimerization of glucuronic acid into iduronic acid adds structural variability to chondroitin/dermatan sulfate polysaccharides. Iduronic acid-containing domains play essential roles in processes such as coagulation, chemokine and morphogen ...
Xanthi N Stachtea +6 more
doaj +1 more source
Increase of Dermatan Sulfate in a Case of Pulmonary Fibrosis
The Tohoku Journal of Experimental Medicine, 1975 The quantity and composition of acid glycosaminoglycans (mucopolysaccharides) were compared between a fibrotic lung and normal lungs. The acid glycosaminoglycans were isolated by proteolysis, fractionation with ethanol and precipitation with cetylpyridinium chloride, and were identified by chromatography, electrophoresis and incubation with ...
Masakichi Motomiya +5 more
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Sequencing the Dermatan Sulfate Chain of Decorin. [PDF]
J Am Chem Soc, 2017 Glycomics represents one of the last frontiers and most challenging in omic analysis. Glycosylation occurs in the endoplasmic reticulum and the Golgi organelle and its control is neither well-understood nor predictable based on proteomic or genomic analysis.
Yu Y +8 more
europepmc +5 more sources
Two Dermatan Sulfate Epimerases Form Iduronic Acid Domains in Dermatan Sulfate [PDF]
Journal of Biological Chemistry, 2009 A second dermatan sulfate epimerase (DS-epi2) was identified as a homolog of the first epimerase (DS-epi1), which was previously described by our group. DS-epi2 is 1,222 amino acids long and has an approximately 700-amino acid N-terminal epimerase domain that is highly conserved between the two enzymes.
Anders Malmström +2 more
openaire +3 more sources