The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics
Microorganisms, 2017 Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
doaj +1 more source
Hunter syndrome revisited [PDF]
Romanian Medical Journal, 2020 Hunter syndrome is the type II of mucopolysaccharidose. With impaired glycosaminoglycan catabolism, heparan and dermatan sulfate accumulate in lysosomes. Multiple organ dysfunction is a consequence of this effect.
Dan Cristian Gheorghe +2 more
doaj +1 more source
Biochemical study of dermatan sulfate glycosaminoglycan in adult male patients with Nyhus type II inguinal hernia [PDF]
, 2011 OBJECTIVE: To compare the amount of the dermatan sulfate glycosaminoglycan between male patients with Nyhus type II inguinal hernias and subjects without inguinal hernia, aged between 20 and 40 years.
Dreyfuss, Juliana Luporini +5 more
core +1 more source
Journal of Biological Chemistry, 2018 During the biosynthesis of chondroitin/dermatan sulfate (CS/DS), a variable fraction of glucuronic acid is converted to iduronic acid through the activities of two epimerases, dermatan sulfate epimerases 1 (DS-epi1) and 2 (DS-epi2).
E. Tykesson +9 more
semanticscholar +1 more source
Radioprotective Effects of Dermatan Sulfate in a Preclinical Model of Oral Mucositis-Targeting Inflammation, Hypoxia and Junction Proteins without Stimulating Proliferation. [PDF]
Int J Mol Sci, 2018 Gruber S +11 more
europepmc +3 more sources
Galactosaminoglycans from normal myometrium and leiomyoma
Brazilian Journal of Medical and Biological Research, 2001 In many tumors, the amount of chondroitin sulfate in the extracellular matrix has been shown to be elevated when compared to the corresponding normal tissue. Nevertheless, the degree of chondroitin sulfate increase varies widely.
A.G.A. Berto +3 more
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Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. [PDF]
, 2017 Amyloid aggregates found in the brain of patients with neurodegenerative diseases, including Alzheimer's and Parkinson's disease, are thought to spread to increasingly larger areas of the brain through a prion-like seeding mechanism.
Esko, Jeffrey D +5 more
core +2 more sources
Isolation of Keratan Sulfate Disaccharide-branched Chondroitin Sulfate E from Mactra chinensis
Bio-Protocol, 2017 Glycosaminoglycans (GAGs) including chondroitin sulfate (CS), dermatan sulfate (DS), heparin (HP), heparan sulfate (HS) and keratan sulfate (KS) are linear, sulfated repeating disaccharide sequences containing hexosamine and uronic acid (or galactose in ...
Kyohei Higashi, Toshihiko Toida
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Chondroitin sulfate, dermatan sulfate, and hyaluronic acid differentially modify the biophysical properties of collagen-based hydrogels. [PDF]
Acta Biomater, 2023 Cortes-Medina M +9 more
europepmc +3 more sources
Angewandte Chemie, EarlyView.Real time STD/SDTD NMR unveils water structuring during UiO‐66 gelation under mild, acid‐free conditions compatible with biomolecule encapsulation. This approach bridges molecular‐scale solvent ordering with macroscopic gel properties, unlocking mechanistic insight for the rational design of MOF gels.
Juan C. Muñoz‐García +5 more
wiley +2 more sources