Results 161 to 170 of about 9,563 (231)

Desaturases and elongases, their diagnostic signifikance and determination of their avtivity

open access: yes, 2017
Předložená bakalářská práce se zabývá významem desaturáz a elongáz v metabolismu mastných kyselin. Jsou zde popsány mechanismy regulace a rozdělení těchto enzymů.
Křehlík, David
core  

Dapagliflozin Attenuates NKCC2 Protein Expression and Alleviates Diabetic Kidney Disease in Salt Loaded‐Hypertensive Diabetic Db/Db Mice

open access: yesFASEB BioAdvances, Volume 8, Issue 10, October 2026.
In salt‐loaded, hypertensive diabetic db/db mice with diabetic kidney disease, dapagliflozin lowered blood pressure and reduced tubular and glomerular injury. Mechanistically, dapagliflozin increased cullin E3 ligase abundance, promoting degradation of NKCC2.
Zenab Shahzad   +5 more
wiley   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

open access: yesInsect Molecular Biology, Volume 35, Issue 5, Page 576-593, October 2026.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez   +1 more
wiley   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti-Colitis Activity. [PDF]

open access: yesAdv Sci (Weinh)
Gao Y   +10 more
europepmc   +1 more source

Lipid Accumulation Promotes Tumorigenic Behaviour of Colorectal Cancer Cells

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Obesity and hyperlipidemia are risk factors for the development and progression of different types of cancer including colorectal cancer (CRC). The underlying mechanisms are only incompletely understood. The aim of this study was to assess the impact of hyperlipidemic conditions on tumorigenic behaviour of CRC cells and the effect of obesity ...
Tatjana Itzenhäuser   +7 more
wiley   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 10, Page 3644-3669, October 2026.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba   +14 more
wiley   +1 more source

Giant viruses encode vitamin K-based redox modules for lipid modification. [PDF]

open access: yesProc Natl Acad Sci U S A
Collins R   +7 more
europepmc   +1 more source

Rates of Evolution Differ Between Cell Types Identified by Single‐Cell RNAseq in Threespine Stickleback

open access: yesMolecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT Rates of evolutionary change vary by gene. While some broad gene categories are highly conserved with little divergence over time, others undergo continuous selection pressure and are highly divergent among populations or species. But such comparative evolutionary studies rely on gene ontology categories that are rarely validated in the study ...
Maria L. Rodgers   +11 more
wiley   +1 more source

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