Results 51 to 60 of about 9,563 (231)

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent WO 2011/006948 A1) [PDF]

, 2011
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid ...
Sayanova, O. V., Napier, J. A., Bauer, J.   +2 more
core  

MicroRNA‐Seq Analysis Reveals a Critical Role for miR‐222 in Bovine Intramuscular Adipogenesis via the DDIT4/mTORC1 Axis

Animal Research and One Health, EarlyView.
Schematic diagram illustrating how miR‐222 promotes bovine intramuscular adipogenesis by targeting DDIT4 to activate the mTORC1 signaling pathway. ABSTRACT Intramuscular fat (IMF) is a key determinant of beef quality, particularly with respect to tenderness, flavor, and juiciness.
Jianbing Tan, Liang Qiu, Zhenghai Zhou, Zhipeng Zhang, Nanfei Wang, Jiangang Hao, Linsen Zan, Wucai Yang   +7 more
wiley   +1 more source

Molecular mechanism of interaction between fatty acid delta 6 desaturase and acyl-CoA by computational prediction

AMB Express, 2022
Keypoints The structure of the Δ6 fatty acid desaturase and substrate complex is modeled. The substrate tunnel and key residues of MpFADS6 catalytic activity are determined. The new insights to determine the mechanism of the membrane-bound desaturases.
Jie Cui, Haiqin Chen, Xin Tang, Hao Zhang, Yong Q. Chen, Wei Chen   +5 more
doaj   +1 more source

Temperature Acclimation of the Picoalga Ostreococcus tauri Triggers Early Fatty-Acid Variations and Involves a Plastidial ω3-Desaturase

Frontiers in Plant Science, 2021
Alteration of fatty-acid unsaturation is a universal response to temperature changes. Marine microalgae display the largest diversity of polyunsaturated fatty-acid (PUFA) whose content notably varies according to temperature.
Charlotte Degraeve-Guilbault, Nattiwong Pankasem, Maurean Gueirrero, Cécile Lemoigne, Frédéric Domergue, Tomonori Kotajima, Iwane Suzuki, Jérôme Joubès, Florence Corellou   +8 more
doaj   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Metabolic and Genetic Determinants of Lipid Metabolism Disruption in Non-Alcoholic Fatty Liver Disease

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020
Aim. To present literature data on the metabolic and genetic mechanisms of impaired fatty acid (FA) synthesis in the development and progression of non-alcoholic fatty liver disease (NAFLD).General findings. NAFLD is a widespread disease progressing from
O. Yu. Kytikova, T. P. Novgorodtseva, Yu. K. Denisenko, D. A. Kovalevsky   +3 more
doaj   +1 more source

Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis

, 2012
Nutrition during development affects risk of future cardiovascular disease. Relatively little is known about whether the amount and type of fat in the maternal diet affect vascular function in the offspring.
Masoodi, Mojgan, Geraldine F Clough, Karen A Lillycrop, Samuel P Hoile, Karen A. Lillycrop, Irvine, Nicola A., Philip C. Calder, Graham C. Burdge, Kelsall, Christopher J., Christopher Torrens (114420), Geraldine F. Clough, Geraldine F. Clough (114433), Christopher J. Kelsall, Lillycrop, Karen A., Calder, Philip C., Mojgan Masoodi (152735), Mark A. Hanson (114427), Hoile, Samuel P., Burdge, Graham C., Christopher J. Kelsall (173702), Mark A Hanson, Christopher J Kelsall, Graham C Burdge, Nicola A. Irvine (173711), Torrens, Christopher, Samuel P. Hoile, Nicola A Irvine, Graham C. Burdge (173729), Philip C Calder, Mojgan Masoodi, Hanson, Mark A., Philip C. Calder (173723), Christopher Torrens, Nicola A. Irvine, Clough, Geraldine F., Mark A. Hanson, Samuel P. Hoile (173705), Karen A. Lillycrop (173718)   +37 more
core   +1 more source

Characterisation and properties of cholesterol desaturases from the ciliate Tetrahymena thermophila [PDF]

, 2005
Live Tetrahymena thermophila transforms exogenous cholesterol into 7,22-bis, dehydrocholesterol (DHC) by desaturation at positions C7(8) and C22(23) of the cholesterol moiety.
Valcarce, German A., Muñoz, Luciana, Nusblat, Alejandro David, Alejandro D. Nusblat, Luciana Muñoz, German A. Valcarce, Nudel, Berta Clara, Clara B. Nudel   +7 more
core   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source