Results 91 to 100 of about 16,875 (201)

Protein Phosphatase 2A: More Than a Passenger in the Regulation of Epithelial Cell–Cell Junctions

Frontiers in Cell and Developmental Biology, 2019
Cell–cell adhesion plays a key role in the maintenance of the epithelial barrier and apicobasal cell polarity, which is crucial for homeostasis. Disruption of cell–cell adhesion is a hallmark of numerous pathological conditions, including invasive ...
Diana Schuhmacher, Jean-Marie Sontag, Jean-Marie Sontag, Estelle Sontag, Estelle Sontag   +4 more
doaj   +1 more source

Transmembrane protein PERP is a component of tessellate junctions and of other junctional and non-junctional plasma membrane regions in diverse epithelial and epithelium-derived cells [PDF]

, 2013
Protein PERP (p53 apoptosis effector related to PMP-22) is a small (21.4 kDa) transmembrane polypeptide with an amino acid sequence indicative of a tetraspanin character.
AH Christensen, B Holthöfer, B Nguyen, BK Straub, Caecilia Kuhn, Christine Grund, CJ Skerrow, CJ Skerrow, CJ Skerrow, CM Borrmann, D Garrod, D Skerrow, E Delva, EP Parrish, G Gorbsky, GJ Giudice, H Mueller, Hans Heid, HH Wacker, HW Kaiser, J Kartenbeck, J Kartenbeck, J Li, K Akat, K Schwechheimer, L Langbein, L Langbein, LA Staehelin, LD Attardi, LM Godsel, M Barth, M Barth, M Haftek, MG Farquhar, MP Demlehner, MR Marques, MR Marques, P Cowin, P Cowin, P Cowin, P Cowin, P Drochmans, R Duden, R Moll, RA Ihrie, RA Ihrie, RA Ihrie, RA Ihrie, RA Quinlan, Ralf Zimbelmann, RL Dusek, RM Hicks, S Goossens, S Pieperhoff, S Rickelt, S Rickelt, S Rickelt, S Rickelt, S Rickelt, S Rickelt, Stefanie Winter-Simanowski, Steffen Rickelt, VG Beaudry, VG Beaudry, VG Beaudry, Werner W. Franke, WW Franke, WW Franke, WW Franke, WW Franke, WW Franke, WW Franke, Y Horiguchi, Yvette Dörflinger   +73 more
core   +1 more source

Desmosome assembly, homeostasis, and desmosomal disease

Cell Health and Cytoskeleton, 2016
Nicola Cirillo1,2 1Melbourne Dental School and Oral Health CRC, The University of Melbourne, Melbourne, VIC, Australia; 2Research Unit, Centre for Innovation, Research, Education, and Health (IRIS), Caposele, Italy Abstract: Cell–cell adhesion is involved in all aspects of tissue behavior in multicellular organisms, from tissue morphogenesis
openaire   +4 more sources

Effective Management of Recalcitrant Hailey–Hailey Disease With Risankizumab

International Journal of Dermatology, EarlyView.
Joy Justice, Adriana Della Porta, Eva Niklinska, Jami L. Miller   +3 more
wiley   +1 more source

Immunological Characterization of the Subunit of the 100 angstrom Filaments from Muscle Cells [PDF]

, 1976
We report the immunological characterization of the subunit of the intermediate sized (100 angstrom) filaments from muscle cells. The protein as isolated from smooth muscle (chicken gizzard) has an apparent molecular weight of 50,000.
Hubbard, Bruce D., Lazarides, Elias
core  

Genetics of human and canine dilated cardiomyopathy [PDF]

, 2015
Cardiovascular disease is a leading cause of death in both humans and dogs. Dilated cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third most common form of cardiac disease in humans and the second most common in dogs.
Cobb, Malcolm, Edwards, Jennifer, Ferguson-Mignan, Thomas F.N., Mongan, Nigel P., Rutland, Catrin S., Simpson, Siobhan   +5 more
core   +5 more sources

Dysregulated proteolytic cascades in Netherton syndrome: from molecular pathology to preclinical drug testing

The Journal of Pathology, Volume 268, Issue 3, Page 249-262, March 2026.
Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou, Evangelos Bisyris, Georgios Pampalakis, Georgia Sotiropoulou   +3 more
wiley   +1 more source

Keratin Retraction and Desmoglein3 Internalization Independently Contribute to Autoantibody-Induced Cell Dissociation in Pemphigus Vulgaris

Frontiers in Immunology, 2018
Pemphigus vulgaris (PV) is a potentially lethal autoimmune disease characterized by blister formation of the skin and mucous membranes and is caused by autoantibodies against desmoglein (Dsg) 1 and Dsg3.
Elisabeth Schlögl, Mariya Y. Radeva, Franziska Vielmuth, Camilla Schinner, Jens Waschke, Volker Spindler, Volker Spindler   +6 more
doaj   +1 more source

Sertoli-germ cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases [PDF]

, 2005
When Sertoli and germ cells were co-cultured in vitro in serum-free chemically defined medium, functional anchoring junctions such as cell-cell intermediate filament-based desmosome-like junctions and cell-cell actin-based adherens junctions (e.g ...
Cheng, CY, Lee, WM, Siu, MKY, Wong, CH
core   +1 more source

Mapping Intestinal Paracellular Perm Eability in Mice: Regional and Cellular Variability Under Physiological and Stimulated Conditions

FASEB BioAdvances, Volume 8, Issue 3, March 2026.
This study analyzed the paracellular permeability of the intestines of healthy mice at a basal level. A new detection method involving tissue incubation for 5 min with luminal fluorescent dyes, such as FM1‐43FX (FM), which bind to accessible plasma (or external) cell membranes, was developed.
Mathilde Miquel, Kadirey Verwaerde, Anissa Edir‐Kibri, Mikael Albin, Florence Blas‐Y‐Estrada, Audrey Samper, Elodie Rousseau‐Bacquie, Hervé Robert, Hélène Eutamène, Vassilia Théodorou, Christine Coméra   +10 more
wiley   +1 more source