Results 81 to 90 of about 12,510 (224)
miR-21 downregulates desmin and disrupts desmosome structures.
, 2014 (A) miR-21 expression reduces desmin levels during CVB3 infection. HL-1 cells were transfected and infected as indicated. Desmin, γ-catenin and β-actin were detected by WB.
Pamela A. Hoodless (52068) +8 more
core +1 more source
Journal of Anatomy, EarlyView.Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury +5 more
wiley +1 more source
, 2020 Desmosomes are a class of cell-cell adhesions whose primary physiological function is to maintain the mechanical integrity of tissues. Morphologically, desmosomes are very distinct protein complexes.
Badu-Nkansah, Kwabena Agyeman
core
Stratifin (14-3-3 σ) limits plakophilin-3 exchange with the desmosomal plaque. [PDF]
PLoS ONE, 2013 Desmosomes are prominent cell-cell adhesive junctions in stratified squamous epithelia and disruption of desmosomal adhesion has been shown to have dramatic effects on the function and integrity of these tissues. During normal physiologic processes, such
Brett J Roberts +2 more
doaj +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT While β‐glucans from plants and yeasts have been extensively studied in weaned piglets, studies examining algae β‐glucans are scarce. Thus, the present study aimed to examine the effects of feeding algae β‐glucan in weaned piglets. Male, 21‐day‐old, weaned crossbred piglets were allotted to three experimental groups, which were fed either an ...
Johanna O. Buckenberger +7 more
wiley +1 more source
Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus
Frontiers in Immunology, 2018 Keratins are crucial for the anchorage of desmosomes. Severe alterations of keratin organization and detachment of filaments from the desmosomal plaque occur in the autoimmune dermatoses pemphigus vulgaris and pemphigus foliaceus (PF), which are mainly ...
Franziska Vielmuth +7 more
doaj +1 more source
Oral wound healing in the elderly: Mechanisms, challenges, and innovations
Periodontology 2000, EarlyView.Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker +7 more
wiley +1 more source
Protein Phosphatase 2A: More Than a Passenger in the Regulation of Epithelial Cell–Cell Junctions
Frontiers in Cell and Developmental Biology, 2019 Cell–cell adhesion plays a key role in the maintenance of the epithelial barrier and apicobasal cell polarity, which is crucial for homeostasis. Disruption of cell–cell adhesion is a hallmark of numerous pathological conditions, including invasive ...
Diana Schuhmacher +4 more
doaj +1 more source
Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma
Veterinary Clinical Pathology, EarlyView.ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal +11 more
wiley +1 more source
KazrinE is a desmosome-associated liprin that colocalises with acetylated microtubules [PDF]
, 2009 Kazrin is a widely expressed, evolutionarily conserved cytoplasmic protein that binds the cytolinker protein periplakin. Multiple functions of kazrin have been reported, including regulation of desmosome assembly, embryonic tissue morphogenesis and ...
F. M. Watt +17 more
core +1 more source