Results 31 to 40 of about 16,875 (201)
The cell-cell junctions of mammalian testes: I. The adhering junctions of the seminiferous epithelium represent special differentiation structures [PDF]
, 2014 The seminiferous tubules and the excurrent ducts of the mammalian testis are physiologically separated from the mesenchymal tissues and the blood and lymph system by a special structural barrier to paracellular translocations of molecules and particles ...
Domke, Lisa M. +8 more
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The genetic background of arrhythmogenic right ventricular cardiomyopathy
Journal of Arrhythmia, 2016 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by degeneration of the right ventricle and ventricular tachycardia originating from the right ventricle.
Seiko Ohno, MD, PhD
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New Data on the Features of Skin Barrier in Hidradenitis Suppurativa
Biomedicines, 2023 Hidradenitis suppurativa (HS) is a Th1/17-driven inflammatory skin disease of the apocrine gland-rich (AGR) skin regions, where keratinocytes seem to be the crucial drivers of the initial pathogenic steps.
Orsolya Somogyi +11 more
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eLife, 2017 Cell junctions are scaffolds that integrate mechanical and chemical signaling. We previously showed that a desmosomal cadherin promotes keratinocyte differentiation in an adhesion-independent manner by dampening Epidermal Growth Factor Receptor (EGFR ...
Nicole Ann Najor +6 more
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Frontiers in Cell and Developmental Biology, 2020 BackgroundRecent studies demonstrated that Aquamin®, a calcium-, magnesium-rich, multi-mineral natural product, improves barrier structure and function in colonoids obtained from the tissue of healthy subjects.
Muhammad N. Aslam +11 more
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Frontiers in Cardiovascular Medicine, 2023 BackgroundArrhythmogenic cardiomyopathy can be caused by genetic variants in desmosomal cadherins. Since cardiac desmosomal cadherins are crucial for cell-cell-adhesion, their correct localization at the plasma membrane is essential.MethodsNine ...
Greta Marie Pohl +9 more
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Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis [PDF]
, 2018 Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways.
Balda, María S. +5 more
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Microscopic Visualization of Cell-Cell Adhesion Complexes at Micro and Nanoscale
Frontiers in Cell and Developmental Biology, 2022 Considerable progress has been made in our knowledge of the morphological and functional varieties of anchoring junctions. Cell-cell adhesion contacts consist of discrete junctional structures responsible for the mechanical coupling of cytoskeletons and ...
Bieke Vanslembrouck +6 more
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Agent-based computational modeling of wounded epithelial cell monolayers [PDF]
, 2004 Computational modeling of biological systems, or ‘in silico biology’ is an emerging tool for understanding structure and order in biological tissues. Computational models of the behavior of epithelial cells in monolayer cell culture have been developed ...
Hill, G. +4 more
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Messages from Mutant Desmosomes [PDF]
Journal of Investigative Dermatology, 2022 Single gene disorders are ideally suited to establish robust genotype‒phenotype correlations and provide excellent opportunities to understand molecular pathomechanisms with relevance to complex disorders. The observation that patients diagnosed with the same causative mutation can present with phenotypic disease variability illustrates the significant
Thomas M. Magin, Mechthild Hatzfeld
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