Results 41 to 50 of about 12,510 (224)

Effective Management of Recalcitrant Hailey-Hailey Disease With Risankizumab. [PDF]

Int J Dermatol
International Journal of Dermatology, Volume 65, Issue 7, Page 1457-1459, July 2026.
Justice J, Della Porta A, Niklinska E, Miller JL.   +3 more
europepmc   +2 more sources

Ultrastructure of Mauthner Cells in Fish Adapted to Long-Duration Vestibular Stimulation and the Effect of Ethanol

Neural Plasticity, 1999
Adaptation or resistance of fish Mauthner cells (M-cells) to long duration (2 h) vestibular stimulation (LDS)was produced by daily brief and gradually increasing vestibular stimulation (training).
Nadezhda R. Tiras, Georgy V. Zherdev, Dmitry A. Moshkov   +2 more
doaj   +1 more source

Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes [PDF]

Journal of Cell Biology, 2011
The desmosomal cadherins, desmogleins (Dsgs) and desmocollins (Dscs), comprise the adhesive core of intercellular junctions known as desmosomes. Although these adhesion molecules are known to be critical for tissue integrity, mechanisms that coordinate their trafficking into intercellular junctions to regulate their proper ratio and distribution are ...
Nekrasova, Oxana E., Amargo, Evangeline V., Smith, William O., Chen, Jing, Kreitzer, Geri E., Green, Kathleen J.   +5 more
openaire   +4 more sources

Dsg1 and Dsg3 Composition of Desmosomes Across Human Epidermis and Alterations in Pemphigus Vulgaris Patient Skin

Frontiers in Immunology, 2022
Desmosomes are important epidermal adhesion units and signalling hubs, which play an important role in pemphigus pathogenesis. Different expression patterns of the pemphigus autoantigens desmoglein (Dsg)1 and Dsg3 across different epidermal layers have ...
Thomas Schmitt, Julia Pircher, Letyfee Steinert, Katharina Meier, Kamran Ghoreschi, Franziska Vielmuth, Daniela Kugelmann, Jens Waschke   +7 more
doaj   +1 more source

ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation

Frontiers in Immunology, 2019
Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. Recently, a genetic variant of the Suppression of tumorigenicity 18 (ST18) promoter was reported to cause ST18 up-regulation, associated with ...
Mariya Y. Radeva, Elias Walter, Ramona Alexandra Stach, Amir S. Yazdi, Amir S. Yazdi, Nicolas Schlegel, Ofer Sarig, Eli Sprecher, Eli Sprecher, Jens Waschke   +9 more
doaj   +1 more source

Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

Frontiers in Medicine, 2022
Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine, Valéria Bumiller-Bini Hoch, Valéria Bumiller-Bini Hoch, Angelica B. Winter Boldt, Detlef Zillikens, Detlef Zillikens, Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Christoph M. Hammers, Christoph M. Hammers, Christoph M. Hammers, Matthias Klinger, Jennifer E. Hundt, Jennifer E. Hundt   +14 more
doaj   +1 more source

Disruption of tuftelin 1, a desmosome associated protein, causes skin fragility, woolly hair and palmoplantar keratoderma [PDF]

, 2023
Desmosomes are dynamic complex protein structures involved in cellular adhesion. Disruption of these structures by loss of function variants in desmosomal genes lead to a variety of skin and heart related phenotypes.
Kramer, Duco, Hoes, Martijn F, Verlouw, Joost AM, Slotman, Johan A, Uitterlinden, André G, Schouten, Marloes, van den Akker, Peter C, Bremer, Jeroen, Saris, Jasper, Oberdorf-Maass, Silke, Vermeer, Mathilde CSC, Romero-Herrera, Pedro H, Verkerk, Annemieke JMH, Andrei, Daniela, Meijer, Hillegonda J, van den Ouweland, Ans MW, Hoogeboom, A Jeannette M, Silljé, Herman HW, Dean, M Christopher, Nijenhuis, Miranda, Diercks, Gilles FH, Pas, Hendri H, Hublin, Jean-Jacques, Stoop, Hans, Giepmans, Ben NG, van der Molen, Marije, Bolling, Maria C, Willemsen, Rob, Arp, Pascal, van der Meer, Peter   +29 more
core  

The Desmosome-Keratin Scaffold Integrates ErbB Family and Mechanical Signaling to Polarize Epidermal Structure and Function

, 2022
While classic cadherin-actin connections in adherens junctions (AJs) have ancient origins, intermediate filament (IF) linkages with desmosomal cadherins arose in vertebrate organisms.
Rübsam, Matthias, Broussard, Joshua A., Green, Kathleen J., Niessen, Carien M., Perez White, Bethany E.   +4 more
core   +1 more source

Immunoadsorption of Desmoglein-3-Specific IgG Abolishes the Blister-Inducing Capacity of Pemphigus Vulgaris IgG in Neonatal Mice

Frontiers in Immunology, 2018
Pemphigus vulgaris (PV) is a potentially life-threatening autoimmune blistering disease which is associated with autoantibodies directed against two desmosomal proteins, desmoglein (Dsg) 3 and 1.
Maxi Hofrichter, Jenny Dworschak, Shirin Emtenani, Jana Langenhan, Fanny Weiß, Lars Komorowski, Detlef Zillikens, Winfried Stöcker, Christian Probst, Enno Schmidt, Enno Schmidt, Stephanie Goletz   +11 more
doaj   +1 more source

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

Advanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang, Liang Shi, MingXia Li, Xiao Han, Jinghan Wang, Guangping Wang, Dan Zou, Bingyang Lu, Liyuan Fan   +8 more
wiley   +1 more source