Adaptation or resistance of fish Mauthner cells (M-cells) to long duration (2 h) vestibular stimulation (LDS)was produced by daily brief and gradually increasing vestibular stimulation (training).
Nadezhda R. Tiras +2 more
doaj +1 more source
Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia. [PDF]
It is generally accepted that the intercalated disc (ICD) required for mechano-electrical coupling in the heart consists of three distinct junctional complexes: adherens junctions, desmosomes and gap junctions. However, recent morphological and molecular
Cheng, Lan +9 more
core +2 more sources
Desmosomes are important epidermal adhesion units and signalling hubs, which play an important role in pemphigus pathogenesis. Different expression patterns of the pemphigus autoantigens desmoglein (Dsg)1 and Dsg3 across different epidermal layers have ...
Thomas Schmitt +7 more
doaj +1 more source
Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes [PDF]
The desmosomal cadherins, desmogleins (Dsgs) and desmocollins (Dscs), comprise the adhesive core of intercellular junctions known as desmosomes. Although these adhesion molecules are known to be critical for tissue integrity, mechanisms that coordinate their trafficking into intercellular junctions to regulate their proper ratio and distribution are ...
Nekrasova, Oxana E. +5 more
openaire +4 more sources
During the pupal stage of moths, a mass of connective tissue develops on the dorsal side of the abdominal nerve cord . The cells, which secrete the fibrous matrix, are originally close together, but as they secrete the matrix, they are pushed apart, with a corresponding decrease in their size .
openaire +2 more sources
Assembly of Desmosomal Cadherins into Desmosomes is Isoform Dependent [PDF]
Desmosomes are intercellular adhesive junctions that exhibit cell- and differentiation-specific differences in their molecular composition. In complex epithelia, desmosomes contain multiple representatives of the desmosomal cadherin family, which includes three desmogleins and three desmocollins.
Ishii, Ken +5 more
openaire +2 more sources
ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation
Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. Recently, a genetic variant of the Suppression of tumorigenicity 18 (ST18) promoter was reported to cause ST18 up-regulation, associated with ...
Mariya Y. Radeva +9 more
doaj +1 more source
Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model
Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine +14 more
doaj +1 more source
Dermatology continues to develop at a steady pace. In the past few years there have been exciting advances in our understanding of skin structure and function in health and disease and progress in genetics, epidemiology, immunology, pharmacology and ...
Boffa, Michael J.
core +1 more source
Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells [PDF]
Proteins of the striatin family (striatins 1–4; sizes ranging from 90 to 110 kDa on SDS-polyacrylamide gel electrophoresis) are highly homologous in their amino acid sequences but can differ in their cell-type-specific gene expression patterns and ...
Dörflinger, Yvette +7 more
core +2 more sources

