Results 61 to 70 of about 16,875 (201)

On the histo-morphological changes of transplantable tumors. [PDF]

open access: yes, 1963
1. When chicken sarcoma virus is serially inoculated on the mouse brain, it loses its carcinogenecity, but when it is inoculated on young chicken, granuloma develops in the liver and lung.
Hamazaki, Yukio   +4 more
core   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

New insights into desmosome regulation and pemphigus blistering as a desmosome-remodeling disease

open access: yesKaohsiung Journal of Medical Sciences, 2013
Desmosomes in keratinocytes are the most important intercellular adhering junctions that provide structural strength for the epidermis. These junctions are connected directly with desmosomal cadherin proteins.
Yasuo Kitajima
doaj   +1 more source

A role for caveolin-1 in desmoglein binding and desmosome dynamics. [PDF]

open access: yes, 2011
Desmoglein-2 (Dsg2) is a desmosomal cadherin that is aberrantly expressed in human skin carcinomas. In addition to its well-known role in mediating intercellular desmosomal adhesion, Dsg2 regulates mitogenic signaling that may promote cancer development ...
Brennan, D   +7 more
core   +2 more sources

The hidden science of haptics: A pedagogical review of tactile evaluation in cosmetics

open access: yesInternational Journal of Cosmetic Science, EarlyView.
This review explores the physiological basis of tactile perception and critically examines classical and emerging sensory methods used in cosmetics, advocating for broader methodological integration and recognition of sensory analysis in the field. Abstract Sensory analysis is a cornerstone of cosmetic development, yet remains underrepresented in peer ...
Morgane Postec   +2 more
wiley   +1 more source

Intermediate Filaments and Polarization in the Intestinal Epithelium

open access: yesCells, 2016
The cytoplasmic intermediate filament cytoskeleton provides a tissue-specific three-dimensional scaffolding with unique context-dependent organizational features.
Richard A. Coch, Rudolf E. Leube
doaj   +1 more source

Apoptotic pathways in the pathogenesis of pemphigus: targets for new therapies [PDF]

open access: yes, 2012
Pemphigus is a group of rare autoimmune blistering diseases of the skin in which autoantibodies to desmosome cadherins, desmogleins, induce loss of cell-cell adhesion (acantholysis).
Lotti, Roberta   +2 more
core   +1 more source

Desmosome assembly and dynamics [PDF]

open access: yesTrends in Cell Biology, 2013
Desmosomes are intercellular junctions that anchor intermediate filaments (IFs) to the plasma membrane, forming a supracellular scaffold that provides mechanical resilience to tissues. This anchoring function is accomplished by specialized members of the cadherin family and associated cytoskeletal linking proteins, which together form a highly ...
Oxana, Nekrasova, Kathleen J, Green
openaire   +2 more sources

An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris [PDF]

open access: yes, 2009
Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by the presence of IgG autoantibodies against Dsg3. Our aim was to investigate the molecular events implicated in the development and localization of apoptosis and acantholysis in ...
España, A. (Agustín)   +5 more
core   +1 more source

Desmosomes in acquired disease [PDF]

open access: yesCell and Tissue Research, 2015
Desmosomes are cell-cell junctions that mediate adhesion and couple the intermediate filament cytoskeleton to sites of cell-cell contact. This architectural arrangement integrates adhesion and cytoskeletal elements of adjacent cells. The importance of this robust adhesion system is evident in numerous human diseases, both inherited and acquired, which ...
Sara N, Stahley, Andrew P, Kowalczyk
openaire   +2 more sources

Home - About - Disclaimer - Privacy