Results 51 to 60 of about 83,038 (344)

Copper‐Catalyzed Three‐Component Selective 1,4‐Amino Oxygenation of 1,3‐Dienes

Angewandte Chemie, EarlyView.
Enclosed is a copper‐catalyzed selective 1,4‐amino oxgenation of 1,3‐dienes with the presence of a strong Brønsted acid. This three‐component transformation offers a novel and powerful approach to construct (E)‐1,4‐allylic amino oxygenated motifs by the simultaneous installation of structurally diverse alkylamines and alcohols directly onto 1,3‐dienes.
Guangshou Feng, Maria K. Velopolcek, Qiu Wang   +2 more
wiley   +2 more sources

Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines

Beilstein Journal of Organic Chemistry, 2013
An Ugi four-component reaction of propargylamine with 3-formylindole and various acids and isonitriles produces adducts which are subjected to a cationic gold-catalyzed diastereoselective domino cyclization to furnish diversely substituted spiroindolines.
Amit Kumar, Dipak D. Vachhani, Sachin G. Modha, Sunil K. Sharma, Virinder S. Parmar, Erik V. Van der Eycken   +5 more
doaj   +1 more source

Diastereoselective Synthesis of Benzoxanthenones

Chemistry – An Asian Journal, 2020
AbstractAn oxidative catalytic vanadium(V) system was developed to access the naturally nonabundant diastereomers of carpanone from the corresponding alkenyl phenol monomer in one pot by tandem oxidation, oxidative coupling, and 4+2 cyclization. This system was applied to the synthesis of two other analogues of carpanone.
William C. Neuhaus, Marisa C Kozlowski
openaire   +3 more sources

Inherently chiral calix[4]arenes via oxazoline directed ortholithiation: synthesis and probe of chiral space

Beilstein Journal of Organic Chemistry, 2014
The diastereoselective oxazoline-directed lithiation of calix[4]arenes is reported with diastereoselective ratios of greater than 100:1 in some instances.
Simon A. Herbert, Laura J. van Laeren, Dominic C. Castell, Gareth E. Arnott   +3 more
doaj   +1 more source

In pursuit of β-amino α-nitro β-trifluoromethyl ketones: nitro-Mannich vs Mannich-type reactions [PDF]

, 2017
The reactivity of alfa-nitro ketones with trifluoromethyl aldimines is studied for the first time. While under nitro-Mannich conditions only the facial stereoselectivity can be controlled, organocatalysed Mannich-type reactions allowed a complete control
Ballini, Ballini, Ballini, Ballini, Bhadury, Carroccia, Carroccia, Chen, Claridge, Córdova, Dighe, Dinér, Donslund, Fioravanti, Fioravanti, Fioravanti, Fioravanti, Fioravanti, Gao, Ghosh, Hatano, Hurd, Ibrahem, Ilies, Kano, Kano, Kelly, Kobayashi, Kokotos, Levy, Merino, Mitsumori, Moteki, Nguyen, Nie, Noble, Parise, Parise, Pelagalli, Stach, Walaszek, Yang, Yin, Zhang, Zhang, Zheng   +45 more
core   +1 more source

Enantio- and Diastereoselective Spiroketalization Catalyzed by Chiral Iridium Complex.

Journal of the American Chemical Society, 2017
Iridium-(P,olefin) complex-catalyzed enantio- and diastereoselective formation of substituted spiroketals from racemic, allylic carbonates is reported, which enables the installation of multiple stereogenic centers in a single operation. The protocol was
J. Hamilton, S. Rössler, E. Carreira
semanticscholar   +1 more source

50 Years of Giese Reaction – a Personal View

Angewandte Chemie, EarlyView.
The Giese‐Reaction celebrates its 50. Birthday, it is a cyclic radical chain reaction centered around C,C‐bond formation in a three component synthesis. This minireview speaks about the birth of the name‐reaction, explains how the complete understanding of its reaction mechanism stimulates new methods in organic synthesis, and why it can proceed in ...
Martin Spichty, Hendrik Zipse, Salem Majouri, Katharina M. Fromm, Bernd Giese   +4 more
wiley   +2 more sources

A Brønsted base-promoted diastereoselective dimerization of azlactones

Beilstein Journal of Organic Chemistry, 2017
A novel Brønsted base system for the diastereoselective dimerization of azlactones using trichloroacetate salts and acetonitrile has been developed. Desired products were obtained in good yields (60–93%) and with up to >19:1 dr after one hour of reaction.
Danielle L. J. Pinheiro, Gabriel M. F. Batista, Pedro P. de Castro, Leonã S. Flores, Gustavo F. S. Andrade, Giovanni W. Amarante   +5 more
doaj   +1 more source

Chiral Potassium Brønsted Base‐Catalyzed Stereoselective Synthesis of 1,3‐Diols via a Tandem Allylic Isomerization/Asymmetric Aldol–Tishchenko Reaction

Advanced Synthesis &Catalysis, EarlyView.
Chiral potassium base catalysts featuring 1,1´‐bi‐2‐naphthol‐derived chiral crown ethers as ligands promote a tandem allylic isomerization/asymmetric aldol‐Tishchenko reaction of allylic alcohols and aldehydes. This method provides enantioenriched 1,3‐diols with excellent diastereoselectivity and high enantioselectivity, thereby expanding the synthetic
Hiroki Ishikawa, Masahiro Sai
wiley   +1 more source

Accessing Molecular Complexity from Methane and Other Gaseous Alkanes via Photocatalytic Cascade Cyclization

Angewandte Chemie, EarlyView.
An iron‐catalyzed protocol for the cascade cyclization of N‐aryl and N‐benzoyl acrylamides promoted by methane and other gaseous alkanes is reported. The current protocol provides an efficient platform for the conversion of feedstock gaseous alkanes into complex and medicinally relevant N‐heterocycles.
Akshay M. Nair, Jose M. Malga, Nicolás Martínez‐Acevedo, Martín Fañanás‐Mastral   +3 more
wiley   +2 more sources