Results 11 to 20 of about 20,507 (274)

Occurrence of Potential Prescribing Cascades After Hospital Discharge: A Cohort Study. [PDF]

open access: yesPharmacoepidemiol Drug Saf
ABSTRACT Purpose A prescribing cascade (PC) occurs when a medication (index) causes an adverse drug reaction (ADR), which is addressed by prescribing additional medication (marker). Medication initiated in the hospital may cause post‐discharge ADRs and PCs, especially when multiple healthcare providers are involved.
Mohammad AK   +7 more
europepmc   +2 more sources

Fast microwave-assisted oxidation of 1,4-dihydropyridines with FeCl 3.SiO 2 [PDF]

open access: yes, 2005
Pyridine derivatives are easily obtained in high yields by microwave-promoted rapid oxidation of the corresponding 1,4-dihydropyridines with ferric chloride hexahydrate and silica gel under solvent-free ...
Alaee, E.   +4 more
core   +1 more source

Photodegradation of nimodipine and felodipine in microheterogeneous systems [PDF]

open access: yes, 2012
Indexación: Web of Science; ScieloThe photochemical behavior of nimodipine (NIMO) and felodipine (FELO), photolabile drugs widely used as antihypertensive calcium channel blockers, is studied in constrained media.
Brito, Julio   +6 more
core   +1 more source

Zinc (II)-Mediated Selective O-Benzylation of 2-Oxo-1,2-Dihydropyridines Systems

open access: yesMolecules, 2018
The selective O-benzylation of 2-oxo-1,2-dihydropyridines plays a critical role in organic synthesis of natural products and biological active molecules.
Qifan Zhou   +5 more
doaj   +1 more source

Benign synthesis of therapeutic agents: domino synthesis of unsymmetrical 1,4-diaryl-1,4-dihydropyridines in the ball-mill

open access: yesGreen Chemistry Letters and Reviews, 2022
The solvent-free preparation of unsymmetrical N-aryl-5,6-unsubstituted-1,4-dihydropyridines (DHPs) by ball-milling was investigated. Three different mechanochemical domino reactions (one-pot/one step or stepwise) were studied, the process parameters ...
Cristina Blazquez-Barbadillo   +5 more
doaj   +1 more source

MODULATION OF CALCIUM CHANNELS IN ARTERIAL SMOOTH-MUSCLE CELLS BY DIHYDROPYRIDINE ENANTIOMERS [PDF]

open access: yes, 1993
The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear ...
Bolton, TB   +3 more
core   +1 more source

Comparison of chemical clustering methods using graph- and fingerprint-based similarity measures [PDF]

open access: yes, 2003
This paper compares several published methods for clustering chemical structures, using both graph- and fingerprint-based similarity measures. The clusterings from each method were compared to determine the degree of cluster overlap. Each method was also
Blankley, C.J.   +2 more
core   +1 more source

Synthesis and anticholinesterase activity of a novel series of acetazolamide condensed 1,4-dihydropyridines

open access: yesCarbon Resources Conversion, 2019
A novel Acetazolamide condensed 1, 4-dihydropyridines was set up by treating of N-(5-acetamido-1, 3, 4-thiadiazol-2-ylsulfonyl)-3-oxobutanamide with an aryl aldehyde and 25–30% alkali with sight amount of barium nitrate as a catalyst. Confirmation of the
Mudduluru Niranjan Babu   +5 more
doaj   +1 more source

Construction of 3,5-dinitrated 1,4-dihydropyridines modifiable at 1,4-positions by a reaction of β-formyl-β-nitroenamines with aldehydes [PDF]

open access: yes, 2015
A novel and efficient method for the synthesis of 4-substituted 3,5-dinitro-1,4-dihydropyridines by a reaction of β-formyl-β-nitroenamines with aldehydes was developed.
1187   +7 more
core   +2 more sources

Photoinduced Removal of Nifedipine Reveals Mechanisms of Calcium Antagonist Action on Single Heart Cells [PDF]

open access: yes, 1985
The currents through voltage-activated calcium channels in heart cell membranes are suppressed by dihydropyridine calcium antagonists such as nifedipine.
Gurney, Alison M.   +2 more
core   +2 more sources

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