Results 21 to 30 of about 20,507 (274)

Antimicrobial Activity of Some Derivatives of 1,4-Dihydropyridines

Journal of Chemistry, 2013
Hantzsch reported the synthesis of functionalized 1,4-dihydropyridines via three-component condensation of an aromatic aldehyde, ketoester, and ammonium hydroxide.
Prabha Mehta, Prabha Verma
doaj   +1 more source

In vitro bactericidal activities of two novel dihydropyridine derivatives against Mycobacterium tuberculosis

Journal of Infection in Developing Countries, 2017
Introduction: Introducing new and effective antitubercular agents is important in tuberculosis control programs. In this study, the in vitro antitubercular activity of two novel 1,4-dihydropyridine derivatives (F-27, Cl-33) were screened against a total
Mehdi Zandhaghighi, Farzin Hadizadeh, Saman Soleimanpour, Zahra Meshkat, Seyed Abdolrahim Rezaee, Mohammad Derakhshan, Kiarash Ghazvini   +6 more
doaj   +1 more source

An Efficient Method for The Synthesis of Dihydropyridine by Hantzsch Reaction with Fe/SiO2 Nano Heterogeneous Catalysts

Bulletin of Chemical Reaction Engineering & Catalysis, 2020
An efficient method for the synthesis of dihydropyridines (DHPs) by Hantzsch reaction with Fe/SiO2 heterogeneous catalysts was developed. The Fe/SiO2 catalysts was prepared by impregnation method.
Ateeq Rahman, P. N. Nehemia, Moola M. Nyambe   +2 more
doaj   +1 more source

The unique reactivity of 5,6-unsubstituted 1,4-dihydropyridine in the Huisgen 1,4-diploar cycloaddition and formal [2 + 2] cycloaddition

Beilstein Journal of Organic Chemistry, 2023
The three-component reaction of isoquinolines, dialkyl acetylenedicarboxylates, and 5,6-unsubstituted 1,4-dihydropyridines in acetonitrile at room temperature afforded functionalized isoquinolino[1,2-f][1,6]naphthyridines in good yields and with high ...
Xiu-Yu Chen, Hui Zheng, Ying Han, Jing Sun, Chao-Guo Yan   +4 more
doaj   +1 more source

Management of hypertension in children and adolescents [PDF]

, 2014
Hypertension has been recognized as an important health issue in the pediatric population over the past years. This emphasizes the need for an organized and effective plan for diagnosis and management. This review provides information to guide physicians
De Bruyne, Pauline, Vande Walle, Johan
core   +1 more source

Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study [PDF]

, 2017
Overexpression of the efflux pump P-glycoprotein (P-gp) is one of the important mechanisms of multidrug resistance (MDR) in many tumor cells. In this study, 26 novel 5-oxo-hexahydroquinoline derivatives containing different nitrophenyl moieties at C-4 ...
Edraki, N., Firuzi, O., Khoshneviszadeh, M., Miri, R., Ranjbar, S., Saso, L., Shahraki, O., Zargari, F.   +7 more
core   +1 more source

New synthetic method for the synthesis of 1,4-dihydropyridine using aminated multiwalled carbon nanotubes as high efficient catalyst and investigation of their antimicrobial properties

Journal of Saudi Chemical Society, 2018
Synthesis of 1,4-dihydropyridines in the presence of aminated multiwalled carbon nanotubes and investigation into their antimicrobial properties were carried out.Amino functionalized carbon nanotubes were prepared through a facile, clean and safe ...
Roya Mahinpour, Leila Moradi, Zohreh Zahraei, Nafiseh Pahlevanzadeh   +3 more
doaj   +1 more source

One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor [PDF]

, 2013
The Bohlmann–Rahtz pyridine synthesis and the Hantzsch dihydropyridine synthesis can be carried out in a microwave flow reactor or using a conductive heating flow platform for the continuous processing of material. In the Bohlmann–Rahtz reaction, the use
Bagley, Mark C, Fusillo, Vincenzo, Jenkins, Robert L, Lubinu, M Caterina, Mason, Christopher   +4 more
core   +2 more sources

Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles

Acta Chimica Slovenica, 2022
The efficient one-pot synthesis of some 1,4-dihydropyridines is described by a condensation reaction of some aldehyde derivatives, ethyl acetoacetate and ammonium acetate in the presence of superparamagnetic manganese ferrite nanoparticles at 80 °C.
Somayeh Moradi, Mohsen Moradian, Hossein Naeimi   +2 more
doaj   +1 more source

STROKE PREVENTION OPPORTUNITIES FOR CARDIOLOGISTS: COMPLEX MANAGEMENT OF ARTERIAL HYPERTENSION (ROLE OF CALCIUM ANTAGONISTS)

Кардиоваскулярная терапия и профилактика, 2013
The paper focuses on the important issue of cardio-cerebral interactions, cardiac comorbidities, and the need for complex therapeutic approaches. While stroke is traditionally regarded as a neurologic problem, cardiologists play an important role in its ...
E. O. Taratukhin
doaj   +1 more source