Results 181 to 190 of about 4,569 (202)

Diosmetin Substituent in Galium verum L. Acting on Venous Thrombosis

2010 4th International Conference on Bioinformatics and Biomedical Engineering, 2010
Galium verum L. is a wild plant from Northeast China, this grass is well known as an excellent food source of vitamin, and it also contains phytochemicals such as chlorogenic acid,salicylic acid and flavone. The present work evaluates the anti-venous thrombosis capacity of hydrophilic extracts of Galium.
Lianrong Du, Ge Wang, Weihong Lu, Haitian Zhao   +3 more
openaire   +1 more source

Diosmetin Promotes Early Embryonic Development in Pigs by Alleviating Oxidative Stress

Molecular Reproduction and Development
ABSTRACTDiosmetin (DIOS), a natural flavonoid monomer derived from lemons and present in various plants such as spearmint and spider moss, exhibits antioxidant, anti‐inflammatory, and antiaging properties. Nonetheless, its impact on early embryonic development in pigs remains unexplored.
Jia-Jun, Ren, Xiu-Wen, Yuan, Zi-Long, Meng, Neng-Hao, Cao, Yong-Nan, Xu, Nam-Hyung, Kim, Ying-Hua, Li   +6 more
openaire   +2 more sources

Diosmetin alleviates liver inflammation by improving liver sinusoidal endothelial cell dysfunction

2023
AbstractBackground & AimsTumor necrosis factor-alpha (TNFα) induces pro-inflammatory activation in liver sinusoidal endothelial cells (LSEC) and liver inflammation. However, knowledge about whether modulating LSEC activation can alleviate liver inflammation is scarce.
Dariusz Żurawek, Natalia Pydyn, Piotr Major, Krzysztof Szade, Katarzyna Trzos, Edyta Kuś, Ewelina Pośpiech, Piotr Małczak, Dorota Radkowiak, Andrzej Budzyński, Stefan Chłopicki, Jolanta Jura, Jerzy Kotlinowski   +12 more
openaire   +1 more source

Diosmetin: An Anti‐Leukemic Flavonoid Targeting the Estrogen Receptor β

The FASEB Journal, 2016
Acute myeloid leukemia (AML) is an aggressive hematological malignancy resulting from the accumulation of immature myeloid cells in the peripheral blood and bone marrow. It is associated with poor prognosis, especially in older patients where the 2‐year survival rate is approximately 10%.
Sarah G. Rota, Alessia Roma, Paul A. Spagnuolo   +2 more
openaire   +1 more source

Targeting SKP2/Bcr-Abl pathway with Diosmetin suppresses chronic myeloid leukemia proliferation

European Journal of Pharmacology, 2020
Bcr-Abl is the primary cause as well as currently key therapeutic target of chronic myeloid leukemia (CML). SKP2, an E3 ligase, is a downstream factor of Bcr-Abl to motivate the cell cycle transition of CML and also found to bind and activate Bcr-Abl in reverse. Therefore, SKP2/Bcr-Abl pathway is an attractive target for CML treatment.
Yuan, Liu, Zhenlong, Shao, Yuning, Liao, Xiaohong, Xia, Chuyi, Huang, Jinchan, He, Tumei, Hu, Cuifu, Yu, Lili, Jiang, Jinbao, Liu, Hongbiao, Huang   +10 more
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ChemInform Abstract: Synthesis of O‐(β‐Hydroxyethyl) Derivatives of Diosmetin.

ChemInform, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
R. MOSQUERA, A. ORJALES
openaire   +1 more source

Diosmetin: A dietary flavone as modulator of signaling pathways in cancer progression

Molecular Carcinogenesis
AbstractFlavonoids, constituting the most extensive category of polyphenols, founds in a variety of plants and comprise over 9000 compounds. Diosmetin, O‐methylated flavone (3’,5,7‐trihydroxy‐4’‐methoxyflavone) of flavonoid aglycone diosmin have witnessed a significant surge in recent years.
Waseem Raza, Abha Meena, Suaib Luqman
openaire   +2 more sources

Sensitive Determination of Diosmetin Using Orange‐Red Fluorescent Copper Nanoclusters

ChemistrySelect
Abstract Diosmetin (Dio) has attracted much attention because of its good pharmacological effects, thus it is necessary to determine its content in scientific research and production. In the study, stable orange‐red copper nanoclusters with 4‐hydroxy‐2‐mercapto‐6‐propylpyrimidine (PTU) as reducing agent and ligand
Xin Yang, Jianhua Kuang, Jingxue Yuan, Yao Feng, Zhengjun Cheng   +4 more
openaire   +1 more source

Diosmetin Attenuates Painful Symptoms Caused by Antineoplastics Paclitaxel and Anastrozole in Mice

Molecular Neurobiology
Cancer patients often experience painful symptoms as an adverse effect resulting from various factors, including antineoplastic therapy. Paclitaxel is a chemotherapeutic agent used to treat solid tumours and, unfortunately, causes acute and chronic peripheral neuropathic pain in patients.
Samuel Felipe Atuati, Gabriela Becker, Sara Marchesan Oliveira   +2 more
openaire   +2 more sources

A validated HPLC determination of the flavone aglycone diosmetin in human plasma

Biomedical Chromatography, 2004
AbstractDiosmetin, 3′,5,7‐trihydroxy‐4′‐methoxyflavone, is the aglycone of the flavonoid glycoside diosmin that occurs naturally in foods of plant origin. Diosmin exhibits antioxidant and anti‐inflammatory activities, improves venous tone and it is used for the treatment of chronic venous insufficiency.
Feras Imad, Kanaze, Melpomeni I, Bounartzi, Ioannis, Niopas   +2 more
openaire   +2 more sources